Khurana Sarbjeet, Gourie-Devi Mandaville
Epidemiology, Institute of Human Behaviour and Allied Sciences (IHBAS), New Delhi, IND.
Neurology, Institute of Human Behaviour and Allied Sciences (IHBAS), New Delhi, IND.
Cureus. 2025 Mar 8;17(3):e80248. doi: 10.7759/cureus.80248. eCollection 2025 Mar.
Parkinson's disease (PD) is the second most prevalent neurodegenerative condition, following Alzheimer's disease. Worldwide, the prevalence of PD differs among various populations and geographical areas. In our nation, there is a paucity of population-based epidemiological research that can effectively ascertain the prevalence of PD. In this review article, we have attempted to examine the prevalence rates gathered from the neuro-epidemiological studies in India. We searched for published articles on the prevalence rate of PD in India from PubMed and Google Scholar, using the keywords "prevalence", "burden", "epidemiology", "Parkinson's disease", and "India". The review includes all the community-based studies that calculated the prevalence rate of PD. There are few community-based studies on the prevalence rate of PD. The observed prevalence rates vary a lot in urban and rural areas; also, urban areas show higher prevalence rates than rural areas. Some studies suggest that Parkinson's disease is more common among males, while others indicate a higher prevalence among females. Almost all research suggests that the prevalence rate increases with age for both males and females. The study carried out at the senior care facility revealed that the elderly had a limited understanding of Parkinson's disease. Epidemiological studies on PD are crucial to expanding our knowledge about PD. Given the variations in regions, ethnic groups, and cultures, conducting a comprehensive nationwide multi-center study is essential to investigate the prevalence and factors contributing to PD. Initiatives to raise awareness about PD are also the need of the hour.
帕金森病(PD)是仅次于阿尔茨海默病的第二大常见神经退行性疾病。在全球范围内,PD的患病率在不同人群和地理区域之间存在差异。在我国,缺乏能够有效确定PD患病率的基于人群的流行病学研究。在这篇综述文章中,我们试图研究从印度神经流行病学研究中收集到的患病率。我们使用关键词“患病率”“负担”“流行病学”“帕金森病”和“印度”,在PubMed和谷歌学术上搜索关于印度PD患病率的已发表文章。该综述包括所有计算PD患病率的基于社区的研究。关于PD患病率的基于社区的研究很少。观察到的患病率在城市和农村地区差异很大;此外,城市地区的患病率高于农村地区。一些研究表明帕金森病在男性中更常见,而另一些研究则表明女性患病率更高。几乎所有研究都表明,男性和女性的患病率都随年龄增长而增加。在老年护理机构进行的研究表明,老年人对帕金森病的了解有限。关于PD的流行病学研究对于扩展我们对PD的认识至关重要。鉴于地区、种族和文化的差异,开展一项全面的全国多中心研究对于调查PD的患病率及其影响因素至关重要。提高对PD认识的举措也是当务之急。