Gailhofer G, Ludvan M, Posawetz-Kresbach M
Wien Klin Wochenschr. 1987 Mar 20;99(6):192-4.
Over the past years pyrimidine analogues have gained an important role within the concept of local therapy of viral infections, in particular in the field of ophthalmology. This report deals with a case of contact allergy to trifluorothymidine in a 15 year-old atopic patient. Since until now only a small number of contact allergic reactions have been reported, the halogenated pyrimidine analogues seem to be weak sensitizers. Cross reactivity within these substances may occur.
在过去几年中,嘧啶类似物在病毒感染局部治疗的理念中发挥了重要作用,尤其是在眼科领域。本报告涉及一名15岁特应性患者对三氟胸苷的接触性过敏病例。由于迄今为止仅报道了少数接触性过敏反应,卤化嘧啶类似物似乎是弱致敏剂。这些物质之间可能会发生交叉反应。