Normandie University, UNICAEN, INSERM, COMETE, Caen , France.
Université de Caen Basse-Normandie, EA4260 CESAMS, Caen, France.
J Appl Physiol (1985). 2018 Jul 1;125(1):167-174. doi: 10.1152/japplphysiol.00595.2017. Epub 2018 Mar 15.
The aim of the study was to test the effect of total sleep deprivation on performance and time-of-day pattern of subjective visual vertical (SVV) and postural control. Nineteen healthy, young participants (4 women and 15 men 21.9 ± 1.2 yr) were engaged in two counterbalanced experimental sessions with or without total sleep deprivation. Oral temperature, Karolinska Sleepiness Scale, and visual analogic scale for fatigue, postural control, and SVV were randomly measured every 4 h, from 0600 to 2200. A linear mixed model was used to capture the effect of time of day and sleep condition as factors. A classical adjusted COSINOR function was then used to modelize this daily variation. After the control night of sleep, SVV as well as oral temperature, sleepiness, and fatigue showed significant time-of-day variation, contrasting with measures of postural control which remained stable across the day. After sleep deprivation, SVV showed no diurnal variation, but its mean deviation value increased by 29%. Postural control capability also decreased after sleep deprivation, with a higher center of pressure surface (+70.4%) and total length (+7.37%) but remained stable throughout the day. These results further confirm the negative effect of sleep loss on postural control capability. Even if a direct relationship cannot be confirmed, the disruption of SVV capacity after sleep deprivation could strongly play a role in postural control capacity changes. Sleep deprivation should be considered as a potent factor involved in balance loss and subsequent fall. NEW & NOTEWORTHY The topic of sleep deprivation and postural control is not understood, with discrepancy among results. This study described that postural control displays a stable level throughout the day and that sleep deprivation, even if it increases postural sway, does not affect this stable diurnal pattern. The modification of the perception of the vertical level after sleep deprivation could strongly play a role in the observed changes in postural control capacity.
这项研究的目的是测试完全睡眠剥夺对表现和主观垂直视觉（SVV）及姿势控制的时间模式的影响。19 名健康的年轻参与者（4 名女性和 15 名男性，21.9±1.2 岁）参与了两项平衡的实验，分别为有完全睡眠剥夺和无完全睡眠剥夺。每隔 4 小时，从 0600 到 2200，随机测量口腔温度、卡罗林斯卡嗜睡量表和疲劳的视觉模拟量表，用于测量姿势控制和 SVV。线性混合模型用于捕获时间和睡眠条件作为因素的影响。然后使用经典的调整 COSINOR 函数来模拟这种日常变化。在控制睡眠的夜晚后，SVV 以及口腔温度、嗜睡和疲劳都表现出明显的时间变化，与姿势控制的测量结果形成对比，后者在一天中保持稳定。在睡眠剥夺后，SVV 没有显示出昼夜变化，但平均偏差值增加了 29%。姿势控制能力在睡眠剥夺后也下降了，中心压力表面增加了 70.4%（+70.4%），总长度增加了 7.37%（+7.37%），但全天保持稳定。这些结果进一步证实了睡眠不足对姿势控制能力的负面影响。即使不能确认直接关系，但睡眠剥夺后 SVV 能力的中断可能在姿势控制能力变化中发挥重要作用。睡眠剥夺应被视为平衡丧失和随后跌倒的一个重要因素。
值得注意的是，睡眠剥夺和姿势控制的话题尚未被完全理解，结果存在差异。本研究描述了姿势控制在一整天中保持稳定水平，并且即使睡眠剥夺增加了姿势摆动，也不会影响这种稳定的昼夜模式。睡眠剥夺后对垂直水平感知的改变可能在观察到的姿势控制能力变化中发挥重要作用。
