Hasan Suhair A O
Department of Pediatrics, Port Sudan Hospital, Sudan.
Sudan J Paediatr. 2017;17(2):68-70. doi: 10.24911/SJP.2017.2.10.
A term, male infant weighing 4.725 kg, was born vaginally to a grand multipara, diabetic mother. The birth was difficult and needed assistance with ventose. At 48 hours of birth, the infant noted to be febrile (temperature of 38.5C) with dry skin. Shortly after that, he developed vomiting, loose motions, irritability, and seizure. Examination revealed a macrosomic, normotensive infant, with slightly prolonged capillary refill time (3 sec), clear lung fields, normal heart sounds, bilaterally palpable renal masses which was ovoid, smooth, and 10 × 5 cm in size. Other systems were normal including normal male genitalia. Investigations were normal, apart from hypoglycaemia (random blood sugar of 48 mg/dl), hyponatraemia (Na = 129 mmol/l), and hyperkalaemia (K = 6.7 mmol/l). A salt loosing congenital adrenal hyperplasia was suspected and the abdominal ultrasound (U/S) scanning showed isolated bilateral adrenal haemorrhage. The infant started on hydrocortisone and fludrocortisone. In conclusion, we here report an isolated adrenal haemorrhage that caused adrenal insufficiency in an infant of diabetic mother.
一名足月男婴,体重4.725千克,经阴道由一位多产次的糖尿病母亲分娩。分娩过程困难,需借助负压吸引器助产。出生48小时时,婴儿出现发热(体温38.5摄氏度)且皮肤干燥。此后不久,他出现呕吐、腹泻、烦躁和惊厥。检查发现该婴儿为巨大儿,血压正常,毛细血管再充盈时间稍延长(3秒),肺部清晰,心音正常,双侧可触及肾脏肿块,呈卵圆形,表面光滑,大小为10×5厘米。其他系统正常,包括男性生殖器正常。检查结果除低血糖(随机血糖48毫克/分升)、低钠血症(钠=129毫摩尔/升)和高钾血症(钾=6.7毫摩尔/升)外均正常。怀疑为失盐型先天性肾上腺皮质增生症,腹部超声扫描显示孤立性双侧肾上腺出血。婴儿开始使用氢化可的松和氟氢可的松治疗。总之,我们在此报告一例孤立性肾上腺出血导致糖尿病母亲所生婴儿肾上腺功能不全的病例。