Aiso M, Shigematsu K, Kebabian J W, Potter W Z, Cruciani R A, Saavedra J M
Brain Res. 1987 Apr 7;408(1-2):281-5. doi: 10.1016/0006-8993(87)90388-x.
We report the regional distribution and characteristics of 125I-SCH 23982 binding to D1 receptors in rat brain using a quantitative autoradiographic technique. The substantia nigra pars reticulata, the caudate putamen, the nucleus accumbens and the olfactory tubercle had a single class of high affinity binding sites for 125I-SCH 23982. Binding sites were also present in a discrete, continuous band connecting the caudate putamen with the substantia nigra.
我们运用定量放射自显影技术报告了大鼠脑中125I-SCH 23982与D1受体结合的区域分布及特征。黑质网状部、尾壳核、伏隔核和嗅结节具有一类对125I-SCH 23982的高亲和力结合位点。结合位点也存在于连接尾壳核与黑质的一条离散、连续的带中。
