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对流行病学研究中伯克森误差产生的警示性评论。

A cautionary comment on the generation of Berkson error in epidemiological studies.

作者信息

Hoffmann Sabine, Guihenneuc Chantal, Ancelet Sophie

机构信息

Institut de Radioprotection et de Sûreté Nucléaire (IRSN), PSE-SANTE/SESANE/LEPID, BP 17, 92262, Fontenay-aux-Roses, France.

Faculté de Pharmacie, Université Paris Descartes, Paris, France.

出版信息

Radiat Environ Biophys. 2018 May;57(2):189-193. doi: 10.1007/s00411-018-0737-6. Epub 2018 Mar 15.

DOI:10.1007/s00411-018-0737-6
PMID:29546458
Abstract

Exposure measurement error can be seen as one of the most important sources of uncertainty in studies in epidemiology. When the aim is to assess the effects of measurement error on statistical inference or to compare the performance of several methods for measurement error correction, it is indispensable to be able to generate different types of measurement error. This paper compares two approaches for the generation of Berkson error, which have recently been applied in radiation epidemiology, in their ability to generate exposure data that satisfy the properties of the Berkson model. In particular, it is shown that the use of one of the methods produces results that are not in accordance with two important properties of Berkson error.

摘要

暴露测量误差可被视为流行病学研究中最重要的不确定性来源之一。当目的是评估测量误差对统计推断的影响或比较几种测量误差校正方法的性能时，能够生成不同类型的测量误差是必不可少的。本文比较了最近在辐射流行病学中应用的两种生成伯克森误差的方法在生成满足伯克森模型特性的暴露数据方面的能力。特别是，结果表明使用其中一种方法产生的结果不符合伯克森误差的两个重要特性。

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Shared and unshared exposure measurement error in occupational cohort studies and their effects on statistical inference in proportional hazards models.职业队列研究中共享和非共享暴露测量误差及其对比例风险模型中统计推断的影响。
PLoS One. 2018 Feb 6;13(2):e0190792. doi: 10.1371/journal.pone.0190792. eCollection 2018.
2
Accounting for Berkson and Classical Measurement Error in Radon Exposure Using a Bayesian Structural Approach in the Analysis of Lung Cancer Mortality in the French Cohort of Uranium Miners.在法国铀矿矿工队列肺癌死亡率分析中，使用贝叶斯结构方法考虑氡暴露中的伯克森误差和经典测量误差。
Radiat Res. 2017 Feb;187(2):196-209. doi: 10.1667/RR14467.1. Epub 2017 Jan 24.
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Bayesian dose-response analysis for epidemiological studies with complex uncertainty in dose estimation.
用于剂量估计存在复杂不确定性的流行病学研究的贝叶斯剂量反应分析。
Stat Med. 2016 Feb 10;35(3):399-423. doi: 10.1002/sim.6635. Epub 2015 Sep 13.
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Radiat Res. 2015 Jan;183(1):27-41. doi: 10.1667/RR13729.1. Epub 2014 Dec 12.
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The performance of functional methods for correcting non-Gaussian measurement error within Poisson regression: corrected excess risk of lung cancer mortality in relation to radon exposure among French uranium miners.功能方法在泊松回归中校正非高斯测量误差的性能：法国铀矿工氡暴露与肺癌死亡率校正超额风险的关系。
Stat Med. 2012 Dec 30;31(30):4428-43. doi: 10.1002/sim.5618. Epub 2012 Sep 21.
6
Impact of measurement error in radon exposure on the estimated excess relative risk of lung cancer death in a simulated study based on the French Uranium Miners' Cohort.基于法国铀矿矿工队列的模拟研究中，氡暴露测量误差对肺癌死亡估计超额相对风险的影响。
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