Waldman J D, Schoen F J, Kirkpatrick S E, Mathewson J W, George L, Lamberti J J
Circulation. 1987 Jul;76(1):109-14. doi: 10.1161/01.cir.76.1.109.
Balloon dilatation (BD) of bioprosthetic valves was investigated in vivo and in vitro. Four children with stenotic bioprosthetic porcine valves in the pulmonary position underwent BD of the valve 10 to 24 months after its insertion. Average valve gradient was reduced from 47.5 to 27 mm Hg. Obstruction at the conduit-branch pulmonary artery connection became apparent after dilatation of the valve. These distal stenoses were also dilated. BD technique was tested in vitro with the use of nonstenotic valves in fresh conduits. No damage to the valve or to the conduit was found when oversized balloons were used in a standard fashion or intentionally inflated until rupture. It is concluded that conduit replacement may be deferred by balloon dilatation of obstructed biological valves and/or a stenotic conduit-pulmonary artery anastomosis.
对生物瓣膜的球囊扩张术(BD)进行了体内和体外研究。4名患有肺动脉位置狭窄生物猪瓣膜的儿童在瓣膜植入后10至24个月接受了瓣膜球囊扩张术。平均瓣膜压差从47.5毫米汞柱降至27毫米汞柱。瓣膜扩张后,管道-分支肺动脉连接处的梗阻变得明显。这些远端狭窄也进行了扩张。使用新鲜管道中的无狭窄瓣膜在体外测试了球囊扩张技术。当以标准方式使用超大球囊或故意充气直至破裂时,未发现瓣膜或管道受损。得出的结论是,通过对阻塞的生物瓣膜和/或狭窄的管道-肺动脉吻合口进行球囊扩张,可以推迟管道置换。