Shikata J, Yamamuro T, Mikawa Y, Iida H, Kobori M
Clin Orthop Relat Res. 1987 Jul(220):111-8.
Six cases of relatively uncommon symptomatic atlantoaxial subluxation in Down's syndrome were treated surgically. In all cases, various congenital osseous anomalies were found. Marked myelopathy was noted in four cases of ossiculum terminale and mild myelopathy in one case of anteroposterior spondyloschisis. Five cases were treated successfully with posterior arthrodesis of C1 to C2 and one from the occiput to C2. Excellent bony union and overall improvement in the patients' symptoms was achieved, with a follow-up period ranging from 11 months to three years and nine months. In cases of symptomatic atlantoaxial subluxation of Down's syndrome, where the spinal cord is at risk, early surgical stabilization is the treatment of choice.
对6例唐氏综合征中相对罕见的有症状寰枢椎半脱位患者进行了手术治疗。所有病例均发现各种先天性骨异常。4例终末小骨患者出现明显脊髓病，1例前后脊椎裂患者出现轻度脊髓病。5例患者通过C1至C2后路关节融合术成功治疗，1例从枕骨至C2进行了手术。随访时间为11个月至3年9个月，实现了良好的骨愈合和患者症状的总体改善。对于唐氏综合征有症状的寰枢椎半脱位，当脊髓有风险时，早期手术稳定是首选治疗方法。
