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一个全面的预测模型:用于酗酒者自杀企图的预测——一项来自全国性 3 年纵向研究的结果。

A comprehensive model of predictors of suicide attempt in heavy drinkers: Results from a national 3-year longitudinal study.

机构信息

Assistance Publique-Hôpitaux de Paris (APHP), Corentin-Celton Hospital, Department of Psychiatry, 92130, Issy-les-Moulineaux, France; INSERM UMR 894, Psychiatry and Neurosciences Center, France; Paris Descartes University, PRES Sorbonne Paris Cité, Paris, France.

Assistance Publique-Hôpitaux de Paris (APHP), Corentin-Celton Hospital, Department of Psychiatry, 92130, Issy-les-Moulineaux, France; INSERM UMR 894, Psychiatry and Neurosciences Center, France.

出版信息

Drug Alcohol Depend. 2018 May 1;186:44-52. doi: 10.1016/j.drugalcdep.2018.01.010. Epub 2018 Mar 7.

Abstract

BACKGROUND

Heavy drinkers are at high risk for suicide attempt and suicide. Multiple factors, when examined in isolation, have been implicated in the risk of suicide attempt in this population. In this report, we present a comprehensive model of the 3-year risk of suicide attempt in heavy drinkers using a longitudinal nationally representative study, the National Epidemiologic Survey on Alcohol and Related Conditions (NESARC; wave 1, 2001-2002; wave 2, 2004-2005).

METHODS

We used structural equation modeling to simultaneously examine effects of four broad groups of clinical factors previously identified as potential predictors of attempted suicides: 1) alcohol use disorder severity, 2) severity of comorbidity, 3) sociodemographic characteristics and 4) help-seeking for alcohol problems. Heavy drinking was defined as drinking 5 or more drinks in a day more than once a week in the month prior to Wave 1.

RESULTS

About 1.5% of the 1573 heavy drinker participants (i.e., 5.1% of the NESARC sample) attempted suicide during the 3-year follow-up period. After adjusting for all other factors, several factors independently predicted attempted suicides: the alcohol use disorder liability factor measured by DSM-IV-TR criteria for alcohol abuse and dependence and two dimensions of psychopathology, the general psychopathology factor accounting for the shared effects of all comorbid psychiatric disorders and the externalizing dimension accounting for the shared effects of comorbid substance use disorders. No other factor predicted this risk in addition.

CONCLUSION

This model may help identify individuals with heavy drinking at high risk of suicide and develop more effective suicide prevention strategies.

摘要

背景

重度饮酒者自杀未遂和自杀的风险很高。当孤立地检查多个因素时,它们与该人群自杀未遂的风险有关。在本报告中,我们使用一项全国代表性的纵向研究——国家酒精流行病学调查和相关条件(NESARC;第 1 波,2001-2002 年;第 2 波,2004-2005 年),呈现一个综合的重度饮酒者 3 年自杀未遂风险模型。

方法

我们使用结构方程模型同时检查了四个广泛的临床因素组的影响,这些因素先前被确定为自杀未遂的潜在预测因素:1)酒精使用障碍严重程度,2)合并症严重程度,3)社会人口统计学特征,4)寻求酒精问题帮助。重度饮酒定义为在第 1 波之前的一个月内,每天饮酒 5 杯或以上且每周超过 1 次。

结果

在 1573 名重度饮酒者参与者(即 NESARC 样本的 5.1%)中,约有 1.5%在 3 年随访期间自杀未遂。在调整了所有其他因素后,几个因素独立地预测了自杀未遂:DSM-IV-TR 标准测量的酒精使用障碍倾向因子,包括酒精滥用和依赖,以及两个精神病理学维度,一般精神病理学因子,解释了所有合并的精神疾病的共同影响,以及外部化维度,解释了合并物质使用障碍的共同影响。没有其他因素可以预测这种风险。

结论

该模型可以帮助识别有自杀风险的重度饮酒者,并制定更有效的自杀预防策略。

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