Epidemiology and Biometry Branch, Division of Epidemiology and Prevention Research, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, 5635 Fishers Lane, Rockville, MD 20852, USA.
FedPoint Systems LLC, Fairfax, VA 22033, USA.
Drug Alcohol Depend. 2018 Jun 1;187:261-269. doi: 10.1016/j.drugalcdep.2018.03.006. Epub 2018 Apr 10.
Little is known about the sociodemographic profiles, the intensity of drinking, the severity of alcohol use disorder (AUD), and psychopathology among individuals with specific patterns of concurrent alcohol and drug use and AUD and other drug use disorders (DUDs) comorbidity.
Data were from the National Epidemiologic Survey on Alcohol and Related Conditions-III. We examined sociodemographic correlates and psychopathology among individuals with specific patterns of concurrent use of alcohol and drug and AUD-DUD comorbidity relative to alcohol use or AUD only, respectively, using multinomial logistic regression. We also examined whether concurrent alcohol and drug use and AUD-DUD comorbidity increased the intensity of drinking and severity of AUD, respectively.
The majority (62.0%) of past-year drinkers used only alcohol. The 12-month prevalence of AUD only was 53.5%. Individuals with concurrent use of alcohol and drugs and AUD-DUD comorbidity were more likely to be men, younger, never/previously married, with lower education and income (odds ratios (ORs) ≥ 1.2). Concurrent use of alcohol and drugs and AUD- DUD comorbidity groups were more likely to experience psychopathology than the alcohol use only and AUD only groups, respectively (ORs ≥ 1.3). The intensity of drinking was greater among the concurrent use groups relative to the alcohol use only group, while the severity of AUD was greater among AUD-DUD comorbidity groups relative to the AUD only group.
Research on consequences and treatment outcome of concurrent use of alcohol and drugs and AUD-DUD comorbidity is warranted to inform the development of more effective prevention/intervention programs.
对于同时使用酒精和药物以及酒精使用障碍和其他药物使用障碍共病的个体的社会人口统计学特征、饮酒强度、酒精使用障碍严重程度和精神病理学，人们知之甚少。
数据来自国家酒精相关状况流行病学调查 III。我们使用多项逻辑回归分别检查了同时使用酒精和药物以及酒精使用障碍和其他药物使用障碍共病的个体与仅使用酒精或仅酒精使用障碍相关的社会人口统计学相关性和精神病理学。我们还检查了同时使用酒精和药物以及酒精使用障碍和其他药物使用障碍共病是否分别增加了饮酒强度和酒精使用障碍的严重程度。
大多数（62.0%）过去一年的饮酒者仅使用酒精。仅酒精使用障碍的 12 个月患病率为 53.5%。同时使用酒精和药物以及酒精使用障碍和其他药物使用障碍共病的个体更可能是男性、年龄较小、从未/以前结婚、受教育程度和收入较低（比值比（OR）≥1.2）。与仅使用酒精和仅酒精使用障碍组相比，同时使用酒精和药物以及酒精使用障碍和其他药物使用障碍共病组更有可能出现精神病理学（OR≥1.3）。与仅使用酒精组相比，同时使用组的饮酒强度更大，而与仅酒精使用障碍组相比，酒精使用障碍和其他药物使用障碍共病组的酒精使用障碍严重程度更大。
需要对同时使用酒精和药物以及酒精使用障碍和其他药物使用障碍共病的后果和治疗结果进行研究，以为更有效的预防/干预计划的制定提供信息。
