Zhang Qing, Xie Si-Ning, Wang Ke, Wang Liang, Du Jiang, Guo Teng-Xian, Jia Wang, Jia Gui-Jun, Zhang Li-Wei, Zhang Jun-Ting, Wu Zhen
Department of Neurosurgery, Beijing Tian tan Hospital, Capital Medical University, Beijing, China; China National Clinical Research Center for Neurological Diseases, Beijing, China; Center of Brain Tumor, Beijing Institute for Brain Disorders, Beijing, China; Beijing Key Laboratory of Brain Tumor, Beijing, China.
Department of Anesthesia, Beijing Tian tan Hospital, Capital Medical University, Beijing, China.
World Neurosurg. 2018 Jun;114:e647-e653. doi: 10.1016/j.wneu.2018.03.045. Epub 2018 Mar 14.
Subependymoma is rare, and little is known about subependymoma with intratumoral hemorrhage.
A retrospective study of subependymoma was performed. Among 61 subependymomas, 4 cases of intratumoral hemorrhage were collected. All 4 cases were pathologically confirmed to be subependymoma and showed a benign character.
After complete subependymoma resection, the 4 patients achieved favorable outcomes. Pathology showed that dilated thin-walled vessels and/or hyalinosis of the vessel walls existed in all 4 cases.
The present series showed that subependymomas with hemorrhage and benign pathology are rare and that surgical treatment results in good prognosis. This series supports the hypothesis that the pathology of vascular degeneration may contribute to subependymoma hemorrhage.