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对局限性前列腺癌男性患者当前手术及非手术治疗选择过程的标准化分析。

A standardized analysis of the current surgical and non-surgical treatment selection process for men with localized prostate cancer.

作者信息

Zhong Wenjie, Haghighi Kayvan, Rathore Prem, Wong Eddy, Mancuso Pascal

机构信息

Department of Urology, Liverpool Hospital, Corner of Elizabeth and Goulburn Street, Liverpool, NSW, 2170, Australia.

出版信息

J Robot Surg. 2018 Jun;12(2):215-221. doi: 10.1007/s11701-018-0796-3. Epub 2018 Mar 16.

DOI:10.1007/s11701-018-0796-3
PMID:29549504
Abstract

Robot-assisted radical prostatectomy to treat localized prostate cancer has increased in popularity, although other options exist, including radiotherapy and active surveillance. The decision about choosing the right treatment has become pertinent for many patients. This literature review aimed to assess the current state-of-the-art regarding decisional aids and the associated decisional outcomes for the purpose of designing a method for both patients and doctors to use to make the best treatment decision for the patient. A literature search was conducted via MEDLINE, Embase, and Web of Science databases using the keywords "prostate" and "cancer" and "impact" and "decisio*" and "treatment." Articles were included that focused on treatment outcomes, decision-making processes, and the use of decisional aids for localized prostate cancer. Articles that investigated prostate cancer in general or prostate cancer screening were excluded, as were articles that were not written in English. Altogether, 13 articles were finally critically reviewed for this study. Results were conflicting regarding the relations between patient factors, use of decisional aids, and decisional outcomes. There was a large gap in the literature regarding the optimal decision-making process for men with localized prostate cancer. The role of currently available decisional aids is limited to helping patients make the right decisions. There is a need to develop a novel decisional aid in which patient-physician discussion-involving evaluation of a spectrum of patient-, doctor-, and treatment-related factors-is included.

摘要

机器人辅助根治性前列腺切除术用于治疗局限性前列腺癌的情况越来越普遍,尽管还有其他选择,包括放射治疗和主动监测。对于许多患者来说,选择正确治疗方法的决定变得至关重要。这篇文献综述旨在评估关于决策辅助工具的当前技术水平以及相关的决策结果,以便设计一种供患者和医生使用的方法,为患者做出最佳治疗决策。通过MEDLINE、Embase和科学网数据库进行文献检索,使用关键词“前列腺”、“癌症”、“影响”、“决策*”和“治疗”。纳入的文章聚焦于局限性前列腺癌的治疗结果、决策过程以及决策辅助工具的使用。排除那些总体研究前列腺癌或前列腺癌筛查的文章,以及非英文撰写的文章。本研究最终对13篇文章进行了严格审查。关于患者因素、决策辅助工具的使用和决策结果之间的关系,结果相互矛盾。关于局限性前列腺癌男性的最佳决策过程,文献中存在很大差距。目前可用的决策辅助工具的作用仅限于帮助患者做出正确决策。有必要开发一种新颖的决策辅助工具,其中包括患者与医生的讨论,涉及对一系列患者、医生和治疗相关因素的评估。

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J Robot Surg. 2018 Jun;12(2):215-221. doi: 10.1007/s11701-018-0796-3. Epub 2018 Mar 16.
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本文引用的文献

1
Patient-Reported Outcomes after Monitoring, Surgery, or Radiotherapy for Prostate Cancer.前列腺癌监测、手术或放疗后的患者报告结局
N Engl J Med. 2016 Oct 13;375(15):1425-1437. doi: 10.1056/NEJMoa1606221. Epub 2016 Sep 14.
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10-Year Outcomes after Monitoring, Surgery, or Radiotherapy for Localized Prostate Cancer.局限性前列腺癌监测、手术或放疗 10 年后的结果。
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Robot-assisted laparoscopic prostatectomy versus open radical retropubic prostatectomy: early outcomes from a randomised controlled phase 3 study.
机器人辅助腹腔镜前列腺切除术与开放式经耻骨后前列腺根治术的比较:一项随机对照 3 期研究的早期结果。
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4
What Is a "Good" Treatment Decision? Decisional Control, Knowledge, Treatment Decision Making, and Quality of Life in Men with Clinically Localized Prostate Cancer.什么是“好的”治疗决策?临床局限性前列腺癌男性的决策控制、知识、治疗决策制定与生活质量
Med Decis Making. 2016 Aug;36(6):714-25. doi: 10.1177/0272989X16635633. Epub 2016 Mar 8.
5
Surgery Versus Radiotherapy for Clinically-localized Prostate Cancer: A Systematic Review and Meta-analysis.手术与放疗治疗局限性前列腺癌的比较:系统评价和荟萃分析。
Eur Urol. 2016 Jul;70(1):21-30. doi: 10.1016/j.eururo.2015.11.010. Epub 2015 Dec 15.
6
Laparoscopic versus Robotic-Assisted Radical Prostatectomy for the Treatment of Localised Prostate Cancer: A Systematic Review.腹腔镜与机器人辅助根治性前列腺切除术治疗局限性前列腺癌的系统评价
Urol Int. 2016;96(4):373-8. doi: 10.1159/000435861. Epub 2015 Jul 18.
7
Decision aids for localized prostate cancer treatment choice: Systematic review and meta-analysis.局部前列腺癌治疗选择的决策辅助工具:系统评价和荟萃分析。
CA Cancer J Clin. 2015 May-Jun;65(3):239-51. doi: 10.3322/caac.21272. Epub 2015 Mar 12.
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The effect of urologist experience on choosing active surveillance for prostate cancer.泌尿科医生的经验对前列腺癌选择主动监测的影响。
World J Urol. 2015 Nov;33(11):1701-6. doi: 10.1007/s00345-015-1528-1. Epub 2015 Mar 12.
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A Decision Aid to Support Informed Choices for Patients Recently Diagnosed With Prostate Cancer: A Randomized Controlled Trial.一种支持前列腺癌新诊断患者做出明智选择的决策辅助工具:一项随机对照试验。
Cancer Nurs. 2015 May-Jun;38(3):E42-50. doi: 10.1097/NCC.0000000000000170.
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Cancer patient and survivor research from the cancer information service research consortium: a preview of three large randomized trials and initial lessons learned.癌症患者和幸存者研究:癌症信息服务研究联盟的展望——三项大型随机试验预览及初步经验教训
J Health Commun. 2013;18(5):543-62. doi: 10.1080/10810730.2012.743629. Epub 2013 Feb 28.