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唐氏综合征与肝炎:携带者状态评估

Down's syndrome and hepatitis: an evaluation of carrier status.

作者信息

Dicks J L, Dennis E S

出版信息

J Am Dent Assoc. 1987 May;114(5):637-9. doi: 10.14219/jada.archive.1987.0146.

DOI:10.14219/jada.archive.1987.0146
PMID:2955013
Abstract

Literature citations show that institutionalized people with Down's syndrome have a significantly higher incidence of positive hepatitis B antigen (HBsAg) than mentally handicapped people who do not have Down's syndrome. A review of 2,136 institutionalized mentally handicapped people in Georgia shows that 27% of residents who have Down's syndrome and 7% of the residents who do not have Down's syndrome tested positive for HBsAg. Forty-nine people with Down's syndrome living in the community were screened for HBsAg. Only one (3%) of 37 of the people who had never lived in an institution tested positive for HBsAg. The implication is that patients with Down's syndrome who have never been institutionalized should be treated no differently than any person in the general population who is not suspected of being a transmitter of an infectious disease.

摘要

文献引用表明,患有唐氏综合征的机构收容人员乙肝表面抗原(HBsAg)阳性率显著高于未患唐氏综合征的智力障碍者。对佐治亚州2136名机构收容的智力障碍者进行的一项回顾显示,患有唐氏综合征的居民中有27%的人HBsAg检测呈阳性,而未患唐氏综合征的居民中这一比例为7%。对49名居住在社区的唐氏综合征患者进行了HBsAg筛查。在37名从未在机构生活过的患者中,只有1人(3%)HBsAg检测呈阳性。这意味着,从未被机构收容过的唐氏综合征患者的治疗方式应与普通人群中未被怀疑为传染病传播者的任何人无异。

相似文献

1
Down's syndrome and hepatitis: an evaluation of carrier status.唐氏综合征与肝炎:携带者状态评估
J Am Dent Assoc. 1987 May;114(5):637-9. doi: 10.14219/jada.archive.1987.0146.
2
Hepatitis B virus infection in an institution for the mentally retarded.一所智障人士机构中的乙型肝炎病毒感染
Am J Epidemiol. 1988 Sep;128(3):629-38. doi: 10.1093/oxfordjournals.aje.a115010.
3
Hepatitis and Down's syndrome.肝炎与唐氏综合征。
Am J Ment Defic. 1976 Jan;80(4):401-6.
4
Hepatitis B vaccination in Down's syndrome and other mentally retarded patients.唐氏综合征及其他智障患者的乙肝疫苗接种
Hepatology. 1984 Jul-Aug;4(4):611-4. doi: 10.1002/hep.1840040406.
5
The prevalence of serological markers, hepatitis B virus DNA and elevated serum amino transferase values in institutionalized mentally handicapped males and females: an epidemiological study of HBV infection in residents with Down's syndrome or other forms of mental deficiency.机构收容的男性和女性智力障碍者中血清学标志物、乙型肝炎病毒DNA及血清转氨酶值升高的患病率:唐氏综合征或其他形式智力缺陷居民中HBV感染的流行病学研究
Eur J Epidemiol. 1988 Sep;4(3):349-56. doi: 10.1007/BF00148923.
6
The prevalence of HBeAg and anti-HBe in an institution for the mentally retarded.一家智障机构中乙肝e抗原和乙肝e抗体的流行情况。
Aust N Z J Med. 1978 Oct;8(5):471-3. doi: 10.1111/j.1445-5994.1978.tb02584.x.
7
Hepatitis A and B in non-institutionalized mentally retarded patients.非机构化智力障碍患者中的甲型和乙型肝炎
Hepatogastroenterology. 1985 Aug;32(4):175-7.
8
Risk of hepatitis B in a ward for mentally retarded HBsAg carriers.智障乙肝表面抗原携带者病房内的乙肝感染风险。
Infection. 1986 Jul-Aug;14(4):170-2. doi: 10.1007/BF01645257.
9
Hepatitis B infection in institutionalized Down's syndrome inmates: a longitudinal study with five hepatitis B virus markers.机构收容的唐氏综合征患者中的乙型肝炎感染:一项针对五种乙肝病毒标志物的纵向研究
Clin Exp Immunol. 1980 Jun;40(3):478-86.
10
[Prognostic value of AFP in chronic carriers of HBsAg with Down's syndrome].[甲胎蛋白在唐氏综合征乙肝表面抗原慢性携带者中的预后价值]
Aten Primaria. 1995 Sep 30;16(5):296-7.

引用本文的文献

1
Altered pro-inflammatory and anti-inflammatory plasma cytokines levels in children with Down's syndrome: A meta-analysis.唐氏综合征患儿血浆促炎和抗炎细胞因子水平的改变:一项荟萃分析。
J Family Med Prim Care. 2021 Oct;10(10):3568-3574. doi: 10.4103/jfmpc.jfmpc_364_21. Epub 2021 Nov 5.
2
Serum albumin in Down Syndrome with and without Alzheimer's Disease.患有和未患有阿尔茨海默病的唐氏综合征患者的血清白蛋白
Ir J Med Sci. 2005 Apr-Jun;174(2):4-8. doi: 10.1007/BF03169121.
3
Down's syndrome and the general practitioner.唐氏综合征与全科医生
J R Coll Gen Pract. 1989 Nov;39(328):470-5.