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滑膜软骨瘤病髋关节置换术后的长期疗效。

Long-Term Outcome of Hip Arthroplasty in the Setting of Synovial Chondromatosis.

机构信息

Department of Orthopedic Surgery, Mayo Clinic, Rochester, Minnesota.

出版信息

J Arthroplasty. 2018 Jul;33(7):2173-2176. doi: 10.1016/j.arth.2018.02.027. Epub 2018 Feb 15.

DOI:10.1016/j.arth.2018.02.027
PMID:29550167
Abstract

BACKGROUND

Synovial chondromatosis (SC) is a rare disease involving cartilaginous metaplasia of synovial tissue. Treatment via synovectomy and loose body removal alone results in elevated recurrence rates, with up to 1 in 5 patients requiring conversion to a hip arthroplasty. The purpose of this study is to investigate outcomes of hip arthroplasty in the setting of SC, focusing on (1) disease-specific survival, (2) implant survivorship and complications, and (3) clinical outcomes.

METHODS

We identified 26 patients with histologically confirmed SC who underwent hip arthroplasty between 1970 and 2015. Mean follow-up and patient age were 10 years (range 2-35) and 55 years (range 26-82), respectively. At the time of arthroplasty, 21 (81%) patients had "active" disease and underwent synovectomy. No constrained acetabular components were used. Six patients (23%) had a preoperative flexion contracture.

RESULTS

The 15-year disease-free survival was 89%. Recurrence occurred in 3 patients at a mean of 0.8 years (range 0.03-1.2) postoperatively. Thirteen patients (50%) sustained a complication [most commonly aseptic loosening (n = 3, 12%)] and 7 required revision surgery. The 10-year and 15-year revision-free survival was 82% and 64%, respectively. Mean Harris Hip Score improved significantly from 50 (range 23-85) preoperatively to 82 (range 44-100) postoperatively (P < .001).

CONCLUSION

Arthroplasty with simultaneous synovectomy provides reliable pain relief and excellent disease-specific survival at long-term follow-up; however, revision and complication rates were high.

摘要

背景

滑膜软骨瘤病(SC)是一种罕见的疾病,涉及滑膜组织的软骨化生。单纯行滑膜切除术和游离体切除的治疗方法会导致复发率升高,多达 1/5 的患者需要转为髋关节置换术。本研究旨在探讨滑膜软骨瘤病行髋关节置换术的效果,重点关注(1)疾病特异性生存率,(2)假体生存率和并发症,以及(3)临床结果。

方法

我们共纳入了 26 例经组织学证实的滑膜软骨瘤病患者,这些患者于 1970 年至 2015 年期间接受了髋关节置换术。平均随访时间和患者年龄分别为 10 年(范围 2-35 年)和 55 年(范围 26-82 岁)。在进行关节置换术时,21 例(81%)患者患有“活动性”疾病,并接受了滑膜切除术。未使用约束性髋臼组件。6 例(23%)患者术前存在屈曲挛缩。

结果

15 年无疾病生存率为 89%。3 例患者在术后 0.8 年(范围 0.03-1.2 年)时出现复发。13 例(50%)患者发生并发症[最常见的是无菌性松动(n=3,12%)],7 例患者需要接受翻修手术。10 年和 15 年的翻修生存率分别为 82%和 64%。术前髋关节 Harris 评分平均为 50 分(范围 23-85 分),术后显著提高至 82 分(范围 44-100 分)(P<0.001)。

结论

同时行滑膜切除术的髋关节置换术可在长期随访中提供可靠的疼痛缓解和良好的疾病特异性生存率,但翻修率和并发症发生率较高。

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