Institute of Life Sciences, Swansea University Medical School, Swansea SA2 8PP, UK.
Trends Biochem Sci. 2018 Apr;43(4):230-232. doi: 10.1016/j.tibs.2018.03.001. Epub 2018 Mar 14.
Affimer proteins can bind to a wide variety of target molecules. They can complement and represent a promising alternative to conventional antibodies as they can target molecules with high affinity, specificity, and stability. In addition, they can be selected and expressed in bacterial and mammalian systems. Affimer protein technology shows promise as a tool in the biologist's arsenal of the future in imaging, diagnostic, and therapeutic applications.
亲和体蛋白可以与多种靶分子结合。它们可以作为传统抗体的一种有前途的替代品,因为它们可以针对具有高亲和力、特异性和稳定性的分子。此外,它们可以在细菌和哺乳动物系统中进行选择和表达。亲和体蛋白技术有望成为未来生物学成像、诊断和治疗应用中生物学家工具库的一个工具。