Elkins K L, Stashak P W, Baker P J
J Immunol. 1987 Aug 1;139(3):695-701.
The ability of transferred antigen-primed immune B cells to induce T cell-mediated suppression of the antibody response to Type III pneumococcal polysaccharide (SSS-III) could be blocked or eliminated by prior treatment of B cells with F(ab')2 anti-Ig or anti-IgM antibodies; however, F(ab')2 anti-IgD antibodies, or M5/114 (monoclonal anti-I-A/E antibody), had no effect on activation of suppression by SSS-III-primed B cells. Thus, cell-associated IgM antibody plays an important role in the activation of suppressor T cells during the antibody response to SSS-III.
转移的抗原致敏免疫B细胞诱导T细胞介导的对III型肺炎球菌多糖（SSS-III）抗体反应抑制的能力，可通过用F(ab')2抗Ig或抗IgM抗体预先处理B细胞来阻断或消除；然而，F(ab')2抗IgD抗体或M5/114（单克隆抗I-A/E抗体）对SSS-III致敏B细胞激活抑制作用没有影响。因此，细胞相关的IgM抗体在对SSS-III的抗体反应过程中，对抑制性T细胞的激活起重要作用。
