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前交叉韧带重建术后的化脓性关节炎:基于移植物保留或移除的临床和功能结果

Septic Arthritis After Anterior Cruciate Ligament Reconstruction: Clinical and Functional Outcomes Based on Graft Retention or Removal.

作者信息

Waterman Brian R, Arroyo William, Cotter Eric J, Zacchilli Michael A, Garcia E'Stephan J, Owens Brett D

机构信息

Department of Orthopaedic Surgery, Wake Forest University School of Medicine, Winston-Salem, North Carolina, USA.

Department of Orthopedic Surgery, William Beaumont Army Medical Center, El Paso, Texas, USA.

出版信息

Orthop J Sports Med. 2018 Mar 1;6(3):2325967118758626. doi: 10.1177/2325967118758626. eCollection 2018 Mar.

Abstract

BACKGROUND

There remains a debate over whether to retain the index anterior cruciate ligament (ACL) graft in the setting of septic arthritis.

PURPOSE

To evaluate and compare clinical outcomes for the treatment of septic arthritis after ACL reconstruction (ACLR) in those with and without early graft retention.

STUDY DESIGN

Case series; Level of evidence, 4.

METHODS

The Military Health System was queried for all ACLR procedures performed between 2007 and 2013. Inclusion criteria required active military status, primary ACLR with secondary septic arthritis, and minimum 24-month surveillance. Demographic, clinical, and surgical variables were evaluated using descriptive statistics and regression analysis for factors influencing selected outcomes.

RESULTS

Of 9511 ACLR procedures, 31 (0.32%) were identified as having secondary septic arthritis requiring urgent arthroscopic irrigation and debridement and intravenous antibiotics (mean, 6.3 weeks). The majority (62%) were treated in the subacute (2 weeks to 2 months) setting. Index ACLR was performed with a hamstring autograft (n = 17, 55%), soft tissue allograft (n = 11, 35%), and patellar tendon autograft (n = 3, 10%). The graft was retained in 71% (n = 22) of patients, while 29% (n = 9) underwent early graft debridement. At a mean 26.9-month follow-up, 48% of patients (n = 15) had returned to the military. Graft removal was not predictive of return to active duty ( = .29). The presence of postoperative complications, including symptomatic postinfection arthritis (22.6%) and arthrofibrosis (9.7%), was the only variable predictive of inability to return to duty (odds ratio, 27.5 [95% CI, 3.24-233.47]; = .002). Seven of 9 patients who underwent graft debridement underwent revision ACLR, and all 7 had stable knees at final follow-up compared with 68% (15/22) in the graft retention group.

CONCLUSION

Arthroscopic debridement with early graft removal and staged revision ACLR remains a viable option for restoring knee stability (100%), although the rate of return to active duty was low in the graft resection group (33%). The risk of knee laxity did not differ based on early graft retention. Time to presentation with graft retention was not associated with a decreased rate of graft laxity.

摘要

背景

对于在脓毒性关节炎情况下是否保留初次前交叉韧带(ACL)移植物仍存在争议。

目的

评估和比较早期保留移植物与未保留移植物的ACL重建(ACLR)术后脓毒性关节炎的临床治疗效果。

研究设计

病例系列;证据等级,4级。

方法

查询军事医疗系统2007年至2013年间进行的所有ACLR手术。纳入标准要求现役军人身份、初次ACLR合并继发性脓毒性关节炎以及至少24个月的随访。使用描述性统计和回归分析评估人口统计学、临床和手术变量,以确定影响所选结果的因素。

结果

在9511例ACLR手术中,31例(0.32%)被确定为患有继发性脓毒性关节炎,需要紧急关节镜冲洗清创和静脉使用抗生素(平均6.3周)。大多数(62%)在亚急性期(2周至2个月)接受治疗。初次ACLR采用腘绳肌自体移植物(n = 17,55%)、软组织异体移植物(n = 11,35%)和髌腱自体移植物(n = 3,10%)。71%(n = 22)的患者保留了移植物,而29%(n = 9)的患者早期进行了移植物清创。平均随访26.9个月时,48%(n = 15)的患者重返军队。移植物切除并不能预测能否重返现役(P = 0.29)。术后并发症的出现,包括有症状的感染后关节炎(22.6%)和关节纤维化(9.7%),是唯一预测无法重返现役的变量(优势比,27.5 [95% CI,3.24 - 233.47];P = 0.002)。9例接受移植物清创的患者中有7例进行了ACLR翻修,与移植物保留组68%(15/22)的患者相比,所有7例在末次随访时膝关节均稳定。

结论

关节镜清创并早期切除移植物以及分期进行ACLR翻修仍然是恢复膝关节稳定性的可行选择(100%),尽管移植物切除组重返现役的比例较低(33%)。基于早期移植物保留情况,膝关节松弛的风险并无差异。移植物保留情况下出现症状的时间与移植物松弛率降低无关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/44e8/5846937/568e7cd6b83b/10.1177_2325967118758626-fig1.jpg

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