El-Kady Rania Abd El-Hamid, ElGuindy Ahmed Mahmoud Fouad
Department of Medical Microbiology and Immunology, Faculty of Medicine, Mansoura University, Mansoura, Egypt.
Department of Pathological Sciences, Fakeeh College for Medical Sciences, Jeddah, Kingdom of Saudi Arabia.
Infect Drug Resist. 2022 Jul 13;15:3779-3789. doi: 10.2147/IDR.S369240. eCollection 2022.
Septic arthritis (SA) of the knee following anterior cruciate ligament reconstruction (ACLR) is considered a catastrophic complication in terms of reduced or loss function of the involved joint. The aims of this study were to gauge the incidence, risk factors, and causative organisms of SA after ACLR.
We conducted a retrospective review of 836 patients who underwent primary ACLR at our institution from October 2018 to September 2021. Patients' demographics, onset of presentation, clinical symptoms, laboratory findings, and management details were obtained from patients' electronic medical records.
Out of the 836 primary ACLRs, 12 were complicated with SA (1.43%). Independent risk factors associated with SA included age (OR; 11.12, 95% CI; 1.3-94.97), obesity (OR; 8.51, 95% CI; 1.02-71.13), and diabetes mellitus (OR; 12.58, 95% CI; 2.39-66.3). was the most frequent culprit organism (66.7%), followed by (25%), and (8.3%). No fungal, mycobacterial, or polymicrobial growth were recovered from synovial fluid cultures. All of the infected cases underwent arthroscopic joint lavage and debridement in the operating room followed by intravenous antibiotics. Graft removal was not done in any of the involved patients, with eradication of infection in all cases.
SA after ACLR is uncommon, with identified in about two-thirds of the patients. Prompt diagnosis and treatment are crucial to avoid graft loss and arthritis-associated joint damage. Orthopedic surgeons should consider rigorous implementation of infection control strategies to minimize the incidence of this devastating morbidity.
前交叉韧带重建(ACLR)术后膝关节化脓性关节炎(SA)被认为是一种灾难性并发症,因为受累关节功能会减退或丧失。本研究的目的是评估ACLR术后SA的发生率、危险因素和致病微生物。
我们对2018年10月至2021年9月在本机构接受初次ACLR的836例患者进行了回顾性研究。从患者的电子病历中获取患者的人口统计学资料、就诊时间、临床症状、实验室检查结果和治疗细节。
在836例初次ACLR中,12例并发SA(1.43%)。与SA相关的独立危险因素包括年龄(比值比[OR];11.12,95%置信区间[CI];1.3 - 94.97)、肥胖(OR;8.51,95% CI;1.02 - 71.13)和糖尿病(OR;12.58,95% CI;2.39 - 66.3)。 是最常见的致病微生物(66.7%),其次是 (25%)和 (8.3%)。滑膜液培养未发现真菌、分枝杆菌或混合菌生长。所有感染病例均在手术室接受关节镜下关节灌洗和清创,随后静脉使用抗生素。所有受累患者均未进行移植物切除,所有病例感染均得以根除。
ACLR术后SA并不常见,约三分之二的患者中发现有 。及时诊断和治疗对于避免移植物丢失和关节炎相关的关节损伤至关重要。骨科医生应考虑严格实施感染控制策略,以尽量减少这种毁灭性疾病的发生率。