以同向性象限盲为表现的原发性抗磷脂综合征
Primary antiphospholipid syndrome presenting with homonymous quadrantanopsia.
作者信息
Yang Hee Kyung, Moon Ki Won, Ji Min Jung, Han Sang Beom, Hwang Jeong-Min
机构信息
Department of Ophthalmology, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, South Korea.
Department of Internal Medicine, Kangwon National University Hospital, Kangwon National University Graduate School of Medicine, Chuncheon, South Korea.
出版信息
Am J Ophthalmol Case Rep. 2018 Mar 8;10:208-210. doi: 10.1016/j.ajoc.2018.03.001. eCollection 2018 Jun.
PURPOSE
To report a case of primary antiphospholipid syndrome presenting with isolated homonymous superior quadrantanopsia.
OBSERVATIONS
A 50-year-old Korean man presented with subjective visual disturbance for 1 month. Visual field testing showed a right homonymous superior quadrantanopsia. Brain magnetic resonance imaging (MRI) revealed an old infarct in his left occipital lobe and multiple lesions in other areas of the brain. Laboratory tests showed a marked increase in serum anti-β2 glycoprotein I antibody, which remained elevated after 12 weeks. He was diagnosed with primary antiphospholipid syndrome and started anticoagulation therapy.
CONCLUSIONS AND IMPORTANCE
This is the first case report of primary antiphospholipid syndrome presenting with isolated homonymous quadrantanopsia. Antiphospholipid syndrome should be considered as a differential diagnosis in patients with homonymous visual field defects accompanying multiple cerebral infarcts.
目的
报告一例以孤立性同向性象限盲为表现的原发性抗磷脂综合征病例。
观察结果
一名50岁的韩国男性出现主观视觉障碍1个月。视野测试显示右侧同向性象限盲。脑部磁共振成像（MRI）显示其左侧枕叶有陈旧性梗死灶，脑部其他区域有多个病灶。实验室检查显示血清抗β2糖蛋白I抗体显著升高，12周后仍居高不下。他被诊断为原发性抗磷脂综合征并开始抗凝治疗。
结论与意义
这是首例以孤立性同向性象限盲为表现的原发性抗磷脂综合征病例报告。对于伴有多发性脑梗死的同向性视野缺损患者，应考虑抗磷脂综合征作为鉴别诊断。
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