Amit Lito M, Song Young-Woong
Global Education Institute, Graduate School, Namseoul University.
Department of Occupational Health, Daegu Catholic University.
J UOEH. 2018;40(1):19-32. doi: 10.7888/juoeh.40.19.
Body surface area (BSA) is an important parameter in the conduct of human exposure studies and in clinical processes in children. The aim of this paper was to compare seven BSA formulas and to find out which of these formulas is appropriate for use with Korean children. Body surface area was calculated according to age, age-group and BMI-group using the height and weight data of Korean children (n = 4899) ages 1 to 18 from Korea National Health and Nutrition Examination Survey (2012-2014). We used the formulas of Banerjee and Bhattacharya (1961), Fujimoto and Watanabe (1969), US EPA (1985), Gehan and George (1970), Boyd (1935), Haycock et al (1978) and Mosteller (1987). The average values of the seven formulas were calculated and used as norm values for comparison. All predictions showed a strong positive correlation with the overall average BSA values. Overestimations were observed on the calculations of Gehan and George (1970), US EPA (1985) and Boyd (1935) formulas. Banerjee and Bhattacharya (1961) and Fujimoto and Watanabe (1969) values showed underestimations and the largest error size of 0.027 m for all ages. BSA estimates of Mosteller (1987) and Haycock et al (1978) were found to be closer to the overall average BSA values with the least error size of 0.004 m. Mosteller's formula is recommended for use in the conduct of human exposure studies and in clinical practice among Korean children, although Haycock et al formula is appropriate for children from 1 to 2 years old.
体表面积（BSA）是人体暴露研究及儿童临床过程中的一个重要参数。本文旨在比较七种体表面积公式，找出其中适用于韩国儿童的公式。利用韩国国家健康与营养检查调查（2012 - 2014年）中1至18岁韩国儿童（n = 4899）的身高和体重数据，根据年龄、年龄组和BMI组计算体表面积。我们使用了Banerjee和Bhattacharya（1961年）、Fujimoto和Watanabe（1969年）、美国环境保护局（1985年）、Gehan和George（1970年）、Boyd（1935年）、Haycock等人（1978年）以及Mosteller（1987年）的公式。计算了这七种公式的平均值，并将其用作比较的标准值。所有预测值与总体平均BSA值均呈现出强烈的正相关。在Gehan和George（1970年）、美国环境保护局（1985年）以及Boyd（1935年）公式的计算中观察到了高估现象。Banerjee和Bhattacharya（1961年）以及Fujimoto和Watanabe（1969年）的值显示出低估，且所有年龄段的最大误差值为0.027平方米。发现Mosteller（1987年）和Haycock等人（1978年）的BSA估计值更接近总体平均BSA值，最小误差值为0.004平方米。尽管Haycock等人的公式适用于1至2岁的儿童，但建议在韩国儿童的人体暴露研究及临床实践中使用Mosteller公式。
