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[医院内皮氏假单胞菌感染。使用离子交换树脂的风险]

[Nosocomial Pseudomonas pickettii infection. Danger of the use of ion-exchange resins].

作者信息

Poty F, Denis C, Baufine-Ducrocq H

出版信息

Presse Med. 1987 Jun 20;16(24):1185-7.

PMID:2955360
Abstract

In a recent nosocomial outbreak of Pseudomonas pickettii infection at the general hospital of Corbeil-Essonnes, France, two patients were moderately affected, but two others, who were diabetic, died of septicemia. The infection was transmitted by 0.05% aqueous solutions of chlorhexidine, the treatment of water for these solutions being the cause of contamination. The ion-exchange resin in the deionization cartridges allowed the surviving bacteria in the city water supply to grow while the bacteriological filters downstream only lowered the contamination level. The 0.05% chlorhexidine aqueous solutions failed to prevent growth up to 4 X 10(6) bacteria/ml. P. pickettii is resistant to aminoglycosides and colistine.

摘要

在法国科尔贝伊-埃松讷综合医院近期发生的一起皮氏假单胞菌医院感染暴发中,两名患者受到中度感染,但另外两名糖尿病患者死于败血症。感染是由0.05%的洗必泰水溶液传播的,这些溶液的水处理是污染的原因。去离子滤筒中的离子交换树脂使城市供水系统中存活的细菌得以生长,而下游的细菌过滤器仅降低了污染水平。0.05%的洗必泰水溶液无法阻止细菌生长至每毫升4×10⁶个。皮氏假单胞菌对氨基糖苷类和多粘菌素耐药。

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