Myung Yujin, Ahn Taeseon, Kim Baek-Kyu, Jeong Jae Hoon, Baek Rong-Min
1 Department of Plastic and Reconstructive Surgery, Seoul National University College of Medicine, Seoul National University Bundang Hospital, Seongnam-si, Gyeonggi-do, Korea.
Cleft Palate Craniofac J. 2018 Apr;55(4):521-527. doi: 10.1177/1055665617732786. Epub 2017 Dec 14.
Anatomical variation and deficits of velocardiofacial syndrome patients are related to unsatisfactory treatment results in surgical correction of speech abnormalities. The main purpose of the article is to investigate the clinical significance of thinned levator veli palatini muscle in VCFS patients.
The authors reviewed medical records of all children with velocardiofacial syndrome who received pharyngeal flap surgery between March 2007 and September 2015. Data including thickness of levator veli palatini in magnetic resonance examination; preoperative velopharyngeal gap size from nasoendoscopy; and preoperative and postoperative speech outcomes were collected.
Total of 36 velocardiofacial syndrome patients with preoperative objective data and postoperative speech outcomes were identified. Preoperative velopharyngeal gap showed significant correlation with thickness of levator veli palatini (correlation coefficient: 0.297/0.397, P = .02/.03) and gap size showed correlation with postoperative speech improvement (0.347/0.413, P = .04/.02). However, muscle thickness showed no correlation with speech outcomes (0.046/0.037, P = .77/.86).
Thinned levator veli palatini muscle in velocardiofacial syndrome patients are related to widened velopharyngeal gap and production of hypernasal speech, and can give negative impact on postoperative surgical outcome of pharyngeal flap surgery.
腭咽面部综合征患者的解剖变异和缺陷与言语异常手术矫正的治疗效果不理想有关。本文的主要目的是研究腭帆提肌变薄在腭咽面部综合征患者中的临床意义。
作者回顾了2007年3月至2015年9月期间接受咽瓣手术的所有腭咽面部综合征患儿的病历。收集的数据包括磁共振检查中腭帆提肌的厚度；鼻内镜检查术前腭咽间隙大小；以及术前和术后的言语结果。
共确定了36例有术前客观数据和术后言语结果的腭咽面部综合征患者。术前腭咽间隙与腭帆提肌厚度呈显著相关（相关系数：0.297/0.397，P = 0.02/0.03），间隙大小与术后言语改善相关（0.347/0.413，P = 0.04/0.02）。然而，肌肉厚度与言语结果无相关性（0.046/0.037，P = 0.77/0.86）。
腭咽面部综合征患者腭帆提肌变薄与腭咽间隙增宽和高鼻音产生有关，并且会对咽瓣手术的术后手术效果产生负面影响。
