Mitsimponas K, Mehmet S, Kennedy R, Shakib K
Royal Free London NHS Foundation Trust.
Oral & Maxillofacial Surgery, London Deanery.
Br J Oral Maxillofac Surg. 2018 May;56(4):249-255. doi: 10.1016/j.bjoms.2018.02.016. Epub 2018 Mar 16.
Idiopathic condylar resorption is a well-documented but poorly-understood pathological entity that predominantly affects young women, particularly during the pubertal growth spurt. Several theories have been proposed to explain its aetiopathogenesis, the most favoured of which are the hormonally mediated theory, the theory of avascular necrosis, and the dysfunctional remodelling theory. The condition is diagnosed by a combination of clinical and radiological data as well as elements from the patient's history. Treatments such as orthognathic surgery, repositioning and stabilisation of the disc, condylectomy and condylar repair with a costochondral graft, or total prosthetic joint reconstruction, have been suggested, but so far, no method has proved superior. Further research is required to better understand the pathophysiology of the condition and identify the optimal treatment.
特发性髁突吸收是一种有充分文献记载但了解甚少的病理实体，主要影响年轻女性，尤其是在青春期生长突增期间。已经提出了几种理论来解释其病因发病机制，其中最受青睐的是激素介导理论、无血管坏死理论和功能失调重塑理论。该病症通过临床和放射学数据以及患者病史中的要素综合诊断。有人提出了诸如正颌手术、盘复位与稳定、髁突切除术以及用肋软骨移植进行髁突修复或全人工关节重建等治疗方法，但迄今为止，尚无一种方法被证明更具优势。需要进一步研究以更好地了解该病症的病理生理学并确定最佳治疗方法。
