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脊髓出血

Spinal Cord Hemorrhage.

作者信息

Shaban Amir, Moritani Toshio, Al Kasab Sami, Sheharyar Ali, Limaye Kaustubh S, Adams Harold P

机构信息

Department of Neurology, University of Iowa Healthcare, Iowa City, Iowa.

Department of Radiology, University of Iowa Healthcare, Iowa City, Iowa.

出版信息

J Stroke Cerebrovasc Dis. 2018 Jun;27(6):1435-1446. doi: 10.1016/j.jstrokecerebrovasdis.2018.02.014. Epub 2018 Mar 16.

Abstract

BACKGROUND AND PURPOSE

Spinal cord hemorrhages are rare conditions that can be classified based on the primary location of bleeding into intramedullary (hematomyelia), subarachnoid hemorrhage (SAH), subdural hemorrhage, and epidural hemorrhage. We conducted a literature review to better understand the presenting symptoms, etiology, diagnosis, and treatment of spinal cord hemorrhages.

METHODS

We performed a literature search using PubMed with the key words spinal hemorrhage, hematomyelia, spinal subarachnoid hemorrhage, spinal subdural hematoma, and spinal epidural hematoma RESULTS: Most commonly, spinal hematomas present with acute onset of pain and myelopathy but a more insidious course also may occur. Spinal SAH may be especially difficult as it may cause cerebral symptoms. The etiologies vary based on the type (location). The most common causes are trauma, iatrogenic causes, vascular malformations, and bleeding diatheses. Management is often aimed toward rapid surgical decompression and correction of the underlying etiology if possible. Conservative management, including administration of large doses of corticosteroids, reversal of anticoagulation, and close monitoring, has been used as bridging for surgical procedure or as the mainstay of treatment for patients with mild or improving symptoms.

CONCLUSIONS

The variable and overlapping presentations of spinal cord hemorrhages make the diagnosis challenging. Maintaining high levels of clinical suspicion and utilizing magnetic resonance imaging may help in making the right diagnosis. Future studies should aim to create standardized outcome grading system and management guidelines for patients with spinal hemorrhage.

摘要

背景与目的

脊髓出血是一种罕见疾病,可根据出血的主要部位分为髓内出血(脊髓血肿)、蛛网膜下腔出血(SAH)、硬膜下出血和硬膜外出血。我们进行了一项文献综述,以更好地了解脊髓出血的临床表现、病因、诊断和治疗。

方法

我们使用PubMed进行文献检索,关键词为脊髓出血、脊髓血肿、脊髓蛛网膜下腔出血、脊髓硬膜下血肿和脊髓硬膜外血肿。结果:脊髓血肿最常见的表现是急性疼痛和脊髓病发作,但也可能有更隐匿的病程。脊髓SAH可能特别棘手,因为它可能导致脑部症状。病因因类型(位置)而异。最常见的原因是创伤、医源性原因、血管畸形和出血性疾病。治疗通常旨在尽快进行手术减压,并尽可能纠正潜在病因。保守治疗,包括大剂量使用皮质类固醇、逆转抗凝以及密切监测,已被用作手术的过渡措施或作为症状轻微或正在改善的患者的主要治疗方法。

结论

脊髓出血的表现多样且相互重叠,这使得诊断具有挑战性。保持高度的临床怀疑并利用磁共振成像可能有助于做出正确诊断。未来的研究应旨在为脊髓出血患者建立标准化的结果分级系统和管理指南。

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