神经页面作为多发性硬化症患者记忆辅助工具的评价:一项随机对照试验。

Evaluation of NeuroPage as a memory aid for people with multiple sclerosis: A randomised controlled trial.

机构信息

Division of Rehabilitation & Ageing, University of Nottingham, Nottingham, UK.

The Oliver Zangwill Centre for Neuropsychological Rehabilitation, Princess of Wales Hospital, Ely, UK.

出版信息

Neuropsychol Rehabil. 2020 Jan;30(1):15-31. doi: 10.1080/09602011.2018.1447973. Epub 2018 Mar 20.

Abstract

Memory problems are reported in 40%-60% of people with multiple sclerosis (MS). These problems affect independence and may limit the ability to benefit from rehabilitation. Our aim was to evaluate the effectiveness of NeuroPage for people with MS living in the community. A multicentre, single-blind, randomised controlled crossover trial was conducted. The intervention comprised the NeuroPage service, which sends reminder messages to mobile phones at pre-arranged times. In the control condition participants received "non-memory texts", that is, messages not aimed at providing a reminder; for example, supplying news headlines or sport updates. Outcome measures were completed using postal questionnaires after each condition. There were 38 participants aged 28 to 72 (mean 48, SD 11) and 10 (26%) were men. There were no significant differences between NeuroPage and control conditions on the Everyday Memory Questionnaire ( = 0.41,  = 0.02). The number of daily diary items forgotten in the NeuroPage condition was significantly less than in the control (9% vs. 31%,  = 0.01,  = -0.64). Psychological distress was less in the NeuroPage condition than control ( = 0.001,  = -0.84). Further evaluation of the effect on everyday memory is required.

摘要

多发性硬化症患者中有 40%-60%报告存在记忆问题。这些问题会影响独立性,并可能限制他们从康复中获益。我们的目的是评估 NeuroPage 对居住在社区中的多发性硬化症患者的有效性。进行了一项多中心、单盲、随机对照交叉试验。干预措施包括 NeuroPage 服务,该服务会在预先安排的时间向手机发送提醒信息。在对照组中,参与者会收到“非记忆文本”,即不旨在提供提醒的信息;例如,提供新闻头条或体育更新。在每个条件结束后,使用邮寄问卷完成结果测量。有 38 名年龄在 28 至 72 岁之间的参与者(平均年龄 48 岁,标准差 11 岁),其中 10 人(26%)为男性。NeuroPage 和对照组在日常记忆问卷上没有显著差异( = 0.41,  = 0.02)。NeuroPage 条件下忘记的日常日记条目数量明显少于对照组(9%对 31%,  = 0.01,  = -0.64)。NeuroPage 条件下的心理困扰比对照组少( = 0.001,  = -0.84)。需要进一步评估对日常记忆的影响。

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