Key Laboratory of Functional Molecular Engineering of Guangdong Province, School of Chemistry and Chemical Engineering , South China University of Technology , Guangzhou , Guangdong 510640 , China.
Org Lett. 2018 Apr 6;20(7):2112-2115. doi: 10.1021/acs.orglett.8b00698. Epub 2018 Mar 20.
A new method for the synthesis of formamides has been developed through electrochemical decarboxylative N-formylation of amines with glyoxylic acid. This protocol provides an efficient approach to formamides with a broad range of functional group tolerance under ambient conditions.
一种新的合成甲酰胺的方法已经通过电化学脱羧 N-甲酰化胺与乙醛酸发展。该协议提供了一种有效的方法来合成甲酰胺与广泛的官能团容忍度在环境条件下。