Choi Mihyun, Lazo Marjorie Z, Kang Minji, Lee Jeehye, Joo Choun-Ki
Department of Ophthalmology, College of Medicine, Seoul St. Mary's Hospital, The Catholic University of Korea, 222, Banpo-daero, Seocho-gu, Seoul, 06591, Republic of Korea.
Catholic Institute for Visual Science, College of Medicine, Seoul St. Mary's Hospital, The Catholic University of Korea, Seoul, Republic of Korea.
BMC Ophthalmol. 2018 Mar 20;18(1):78. doi: 10.1186/s12886-018-0742-1.
The present study aimed to evaluate the degree of anterior capsule contraction (capsulorhexis contraction) with three different single-piece, hydrophilic acrylic intraocular lenses (IOLs).
Patients were prospectively randomized to be implanted with one of three types of IOLs during cataract surgery: the Ophtec Precizon (IOL A), the Lucid Korea Microflex (IOL B), and the Carl Zeiss Asphina (IOL C). One week, 2 weeks, and 6 months after surgery, the area of the anterior capsule opening was measured using digital retro-illumination images after dilation of the pupil. The data were then evaluated using POCOman software.
The study included 236 eyes of 202 patients. The area of the anterior capsule opening reduced by 3.53 ± 3.31 mm (17.06% ± 15.99%) between 1 week and 2 months post-operatively in the IOL A group, by 0.62 ± 1.32 mm (2.87% ± 6.03%) in the IOL B group, and by 1.09 ± 1.53 mm (4.72% ± 6.10%) in the IOL C group. The IOL B group showed minimal anterior capsule contraction 2 months after surgery (p < 0.001).
IOLs with a four-plate haptic design (IOL B) showed more anterior capsular stability than those with a two-loop plate haptic (IOL A) or two-plate haptic (IOL C) design. The number and position of haptics in a capsular bag may affect anterior capsule contraction. We assume that supporting the zonules evenly may play a role in anterior capsular stability.
Current Controlled Trials ISRCTN76566080 , Retrospectively registered (Date of registration: 14 Feb 2018).
本研究旨在评估三种不同的单片式亲水性丙烯酸人工晶状体（IOL）的前囊收缩程度（撕囊收缩）。
患者在白内障手术期间被前瞻性随机分配植入三种IOL中的一种：Ophtec Precizon（IOL A）、Lucid Korea Microflex（IOL B）和Carl Zeiss Asphina（IOL C）。术后1周、2周和6个月，在瞳孔散大后使用数字后照图像测量前囊开口面积。然后使用POCOman软件评估数据。
该研究纳入了202例患者的236只眼。IOL A组术后1周与2个月之间前囊开口面积减少了3.53±3.31mm（17.06%±15.99%），IOL B组减少了0.62±1.32mm（2.87%±6.03%），IOL C组减少了1.09±1.53mm（4.72%±6.10%）。IOL B组在术后2个月时前囊收缩最小（p<0.001）。
具有四板袢设计的IOL（IOL B）比具有双袢板袢（IOL A）或双板袢（IOL C）设计的IOL表现出更高的前囊稳定性。囊袋中袢的数量和位置可能会影响前囊收缩。我们认为均匀地支撑悬韧带可能在前囊稳定性中起作用。
国际标准随机对照试验编号ISRCTN76566080，回顾性注册（注册日期：2018年2月14日）。
