Department of Family Medicine, American University of Beirut Medical Center, Hamra, Beirut, Lebanon.
Faculty of Medicine, American University of Beirut Medical Center, Beirut, Lebanon.
BMC Prim Care. 2022 May 2;23(1):98. doi: 10.1186/s12875-022-01707-w.
This study aims to examine the sleep pattern and predictors of daily vs. as-needed use of hypnotics in middle-aged and older adults with insomnia.
Patients aged 50-75 who use hypnotics for insomnia were identified via electronic medical records and were recruited. Data about sociodemographics, mood and cognitive screening measures, and questions related to sleep patterns were collected through an interview conducted over the phone.
A sample of 66 participants was recruited, of which 69.7% were females. Three quarters (49/66, 74.2%) used hypnotics daily, with 43% (21/49) of daily hypnotics users sleeping more than 8 h per night. Two-fifths (26/66, 39.4%) of participants still had clinically significant insomnia even after taking hypnotics. After adjusting for age, years of hypnotics use, sleeping hours per night, PHQ-2 score, and frequency of pain at night, the logistic regression model showed that younger age (p = 0.023) and longer sleeping hours per night (p = 0.025) were significantly associated with daily hypnotics use when compared to as needed hypnotics use.
Many hypnotic users still have clinically significant insomnia and poor quality of sleep as reflected by perceived longer sleep duration and more daytime napping which could be related to drug-related residual sedation. Hypnotic use may not be the best solution for insomnia treatment in an older population, and physicians should regularly reassess the use of hypnotics.
本研究旨在调查中年和老年失眠患者的睡眠模式和按需使用催眠药物的预测因素。
通过电子病历识别并招募使用催眠药物治疗失眠的 50-75 岁患者。通过电话访谈收集有关社会人口统计学、情绪和认知筛查措施以及与睡眠模式相关问题的数据。
共招募了 66 名参与者,其中 69.7%为女性。四分之三(49/66,74.2%)的人每天使用催眠药物,其中 43%(21/49)的人每晚睡眠时间超过 8 小时。五分之二(26/66,39.4%)的参与者即使服用催眠药物仍存在临床显著失眠。在校正年龄、催眠药物使用年限、每晚睡眠时间、PHQ-2 评分和夜间疼痛频率后,逻辑回归模型显示,与按需使用催眠药物相比,年龄较小(p=0.023)和每晚睡眠时间较长(p=0.025)与每日使用催眠药物显著相关。
许多催眠药物使用者仍存在临床显著失眠和睡眠质量差的情况,表现为睡眠时间较长和白天打盹较多,这可能与药物相关的残留镇静作用有关。催眠药物治疗可能不是老年人群失眠治疗的最佳方法,医生应定期重新评估催眠药物的使用情况。