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一例具有挑战性的急性汞中毒病例。

A Challenging Case of Acute Mercury Toxicity.

作者信息

Nayfeh Ali, Kassim Thamer, Addasi Noor, Alghoula Faysal, Holewinski Christopher, Depew Zachary

机构信息

Department of Internal Medicine, Creighton University, Omaha, NE, USA.

Catholic Health Initiative (CHI), Englewood, CO, USA.

出版信息

Case Rep Med. 2018 Feb 18;2018:1010678. doi: 10.1155/2018/1010678. eCollection 2018.

Abstract

BACKGROUND

Mercury exists in multiple forms: elemental, organic, and inorganic. Its toxic manifestations depend on the type and magnitude of exposure. The role of colonoscopic decompression in acute mercury toxicity is still unclear. We present a case of acute elemental mercury toxicity secondary to mercury ingestion, which markedly improved with colonoscopic decompression.

CLINICAL CASE

A 54-year-old male presented to the ED five days after ingesting five ounces (148 cubic centimeters) of elemental mercury. Examination was only significant for a distended abdomen. Labs showed elevated serum and urine mercury levels. An abdominal radiograph showed radiopaque material throughout the colon. Succimer and laxatives were initiated. The patient had recurrent bowel movements, and serial radiographs showed interval decrease of mercury in the descending colon with interval increase in the cecum and ascending colon. Colonoscopic decompression was done successfully. The colon was evacuated, and a repeat radiograph showed decreased hyperdense material in the colon. Three months later, a repeat radiograph showed no hyperdense material in the colon.

CONCLUSION

Ingested elemental mercury can be retained in the colon. Although there are no established guidelines for colonoscopic decompression, our patient showed significant improvement. We believe further studies on this subject are needed to guide management practices.

摘要

背景

汞以多种形式存在,即元素汞、有机汞和无机汞。其毒性表现取决于接触的类型和程度。结肠镜减压在急性汞中毒中的作用仍不明确。我们报告一例因摄入汞导致的急性元素汞中毒病例,经结肠镜减压后病情明显改善。

临床病例

一名54岁男性在摄入5盎司(148立方厘米)元素汞五天后就诊于急诊科。检查仅发现腹部膨隆。实验室检查显示血清和尿液汞水平升高。腹部X线片显示整个结肠有不透射线物质。开始使用二巯丁二酸和泻药。患者反复排便,系列X线片显示降结肠内汞含量逐渐减少,盲肠和升结肠内汞含量逐渐增加。成功进行了结肠镜减压。结肠内物质排空,复查X线片显示结肠内高密度物质减少。三个月后,复查X线片显示结肠内无高密度物质。

结论

摄入的元素汞可滞留在结肠内。尽管目前尚无关于结肠镜减压的既定指南,但我们的患者病情有显著改善。我们认为需要对此主题进行进一步研究以指导管理实践。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a451/5835301/45b9efcdfe73/CRIM2018-1010678.001.jpg

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