Danchin N, Cornette A, Henriquez A, Godenir J P, Ethevenot G, Polu J M, Sadoul P
Chest. 1987 Aug;92(2):229-33. doi: 10.1378/chest.92.2.229.
A consecutive series of 40 patients (39 men, one woman; mean age 54.1 +/- 8.2 years) with chronic obstructive lung disease (COLD) underwent right heart catheterization and 2-D echocardiographic examination within 72 hr. An adequate 2-D echocardiographic study was obtained in 32 patients (80 percent) using the apical and/or subcostal views. Mean pulmonary artery pressure at rest and during exercise were correlated with right ventricular diameters and areas in end-systole and end-diastole (r = 0.63 to 0.73). Correlations between right ventricular free wall thickness and pulmonary artery pressure were weak (r = 0.51 and 0.57). Right ventricular end-diastolic pressure was also weakly correlated with right ventricular dimensions (r = 0.45 to 0.51), whereas right ventricular area fractional shortening was not correlated with hemodynamic parameters. Patients with previous episode of right heart failure had larger right ventricles than those without such episodes. Thus, 2-D echocardiography appears useful to study the right heart chambers in patients with COLD.
对连续的40例慢性阻塞性肺疾病(COLD)患者(39例男性,1例女性;平均年龄54.1±8.2岁)在72小时内进行了右心导管检查和二维超声心动图检查。32例患者(80%)采用心尖和/或肋下视图获得了充分的二维超声心动图研究。静息和运动时的平均肺动脉压与收缩末期和舒张末期右心室直径及面积相关(r = 0.63至0.73)。右心室游离壁厚度与肺动脉压之间的相关性较弱(r = 0.51和0.57)。右心室舒张末期压力与右心室尺寸也呈弱相关(r = 0.45至0.51),而右心室面积缩短分数与血流动力学参数无相关性。有右心衰竭既往史的患者右心室比无此类病史的患者更大。因此,二维超声心动图似乎有助于研究COLD患者的右心腔。