Laird-Meeter K, van Domburg R, Bos E, Hugenholtz P G
Eur Heart J. 1987 May;8(5):449-56. doi: 10.1093/oxfordjournals.eurheartj.a062304.
To evaluate longterm survival, 1041 consecutive patients with aorto-coronary bypass operations were followed for a mean of 7.5 years (range 5 to 14.5). The peri-operative mortality was 12 (1.2%). Of the 131 late deaths, 97 (74%) were cardiac in origin. The survival probability at 5 years was 92 +/- 2% and at 10 years 79 +/- 4%. Figures for a matched general Dutch population are 94% and 87%, respectively. Stepwise multivariate analysis revealed an association between death rate and impaired left ventricular function (rate ratio impaired function versus normal: 1.82, P = 0.0007) and extent of vascular disease (rate ratio 3 vessel-versus 1 vessel disease: 1.80, P = 0.01) while no relation was found with sex or age at operation. Surgery seems to provide a good probability of survival, although in patients with extensive vascular involvement and/or a decreased left ventricular function at the time of operation, the longterm outlook is less favourable than for those without these characteristics.
为评估长期生存率，对1041例连续接受主动脉冠状动脉搭桥手术的患者进行了平均7.5年（范围5至14.5年）的随访。围手术期死亡率为12例（1.2%）。在131例晚期死亡病例中，97例（74%）源于心脏疾病。5年生存率为92±2%，10年生存率为79±4%。与之匹配的荷兰普通人群的相应数字分别为94%和87%。逐步多变量分析显示死亡率与左心室功能受损（功能受损与正常的率比：1.82，P = 0.0007）以及血管疾病程度（三支血管病变与单支血管病变的率比：1.80，P = 0.01）之间存在关联，而未发现与性别或手术时年龄有关。手术似乎能提供较好的生存概率，不过对于手术时伴有广泛血管病变和/或左心室功能下降的患者，其长期预后不如没有这些特征的患者。
