Coll-Mazzei J, Devolfe C, Adeleine P, Jegaden O, Malquarti V, Boukili A, el Kirat A M, Mikaeloff P
J Cardiovasc Surg (Torino). 1986 Nov-Dec;27(6):650-6.
The 10-year follow-up of consecutive series of 126 patients who underwent coronary bypass surgery from January 1970 through December 1972 without associated procedures is reported. There were 112 men and 14 women with a mean age of 50.3 +/- 8.0 years. Indications for operation were stable angina pectoris in 35 cases and unstable angina in 91 cases. Eleven patients had one-vessel disease, 55 patients had two-vessel disease and 60 patients had three-vessel disease. The mean number of grafts per patient was 1.8. Graft patency rate was 78.4% at the time of early angiographic control (from one to 24 months). There were two early deaths and 47 late deaths. One patient was last to follow-up. Twenty-six of the late deaths were cardiac in nature (57.7%). The overall 10-year survival rate was 68.0 +/- 4.1%. The factors most clearly related to survival rate were: age (p less than 0.05) ischaemic ST-segment depressions on resting preoperative electrocardiogram (p less than 0.005), preoperative electrocardiographic evidence of anterior, septal or lateral myocardial infarction (p less than 0.05), ventricular function as assessed by preoperative left ventriculography (p less than 0.05). During the follow-up period 35.1% of survivors had had no recurrence of angina and 64.9% had experienced at least one episode of angina. At the ten-year evaluation 33 surviving patients considered themselves free of angina, 27 patients considered the angina to be less severe than before the operation and four considered it to be the same or more severe. A significant positive correlation was noted between clinical response and completeness of revascularization (p less than 0.05).
报告了1970年1月至1972年12月期间连续126例接受冠状动脉搭桥手术且无相关手术的患者的10年随访情况。其中男性112例，女性14例，平均年龄50.3±8.0岁。手术指征为稳定型心绞痛35例，不稳定型心绞痛91例。11例患者为单支血管病变，55例患者为双支血管病变，60例患者为三支血管病变。每位患者的平均移植血管数为1.8。早期血管造影检查（1至24个月）时移植血管通畅率为78.4%。有2例早期死亡和47例晚期死亡。1例患者失访。26例晚期死亡为心源性（57.7%）。总体10年生存率为68.0±4.1%。与生存率最明显相关的因素为：年龄（p<0.05）、术前静息心电图缺血性ST段压低（p<0.005）、术前心电图显示前壁、间隔或侧壁心肌梗死（p<0.05）、术前左心室造影评估的心室功能（p<0.05）。在随访期间，35.1%的幸存者无心绞痛复发，64.9%至少经历过一次心绞痛发作。在10年评估时，33例存活患者认为自己无心绞痛，27例患者认为心绞痛比手术前减轻，4例患者认为与术前相同或加重。临床反应与血运重建完整性之间存在显著正相关（p<0.05）。
