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一项针对巴西儿科人群口腔颌面部活检病变的多中心研究。

A multicenter study of biopsied oral and maxillofacial lesions in a Brazilian pediatric population.

作者信息

Silva Leni Verônica de Oliveira, Arruda José Alcides Almeida, Martelli Stephanie Joana, Kato Camila de Nazaré Alves de Oliveira, Nunes Laiz Fernanda Mendes, Vasconcelos Ana Carolina Uchoa, Tarquinio Sandra Beatriz Chaves, Gomes Ana Paula Neutzling, Gomez Ricardo Santiago, Mesquita Ricardo Alves, Silveira Marcia Maria Fonseca da, Sobral Ana Paula Veras

机构信息

Universidade Federal de Minas Gerais - UFMG, School of Dentistry, Department of Oral Surgery and Pathology, Belo Horizonte, MG, Brazil.

Universidade Federal de Pelotas - UFPel, School of Dentistry, Diagnostic Center for Oral Diseases, Pelotas, RS, Brazil.

出版信息

Braz Oral Res. 2018 Mar 15;32:e20. doi: 10.1590/1807-3107bor-2018.vol32.0020.

DOI:10.1590/1807-3107bor-2018.vol32.0020
PMID:29561950
Abstract

The aim of this study was to investigate the prevalence of oral and maxillofacial lesions among children from representative regions of Brazil. A retrospective descriptive study was conducted. Biopsy records comprising the period from 2000 to 2015 were obtained from the archives of three Brazilian oral pathology referral centers. A total of 32,506 biopsy specimens were analyzed, and specimens from 1,706 children aged 0-12 years were selected. Gender, age, anatomical location and histopathological diagnosis were evaluated. Descriptive statistics was carried out. Likelihood ratio tests were used to evaluate the association between the categorical variables. The level of significance was set at 0.05. The post-hoc test was used to identify the subgroups that significantly differed from one another, and the Bonferroni correction was applied. A total of 1,706 oral and maxillofacial lesions were diagnosed in pediatric patients, including 51.9% girls. Oral mucocele was the most prevalent reactive/inflammatory lesion (64%). The most commonly affected sites were the lips (34.5%) and mandible (19.9%). A significant association was observed between age and the group of lesions of the oral cavity (p < 0.001), and between age and anatomical location (p < 0.001). Pediatric oral and maxillofacial lesions were frequent and showed wide diversity, with the prevalence of mucocele. Knowledge of oral lesions is important for pediatric dentists worldwide, since it provides accurate data for the diagnosis and oral health of children.

摘要

本研究的目的是调查巴西代表性地区儿童口腔颌面部病变的患病率。开展了一项回顾性描述性研究。从巴西三个口腔病理学转诊中心的档案中获取了2000年至2015年期间的活检记录。共分析了32506份活检标本,并选取了1706名0至12岁儿童的标本。对性别、年龄、解剖位置和组织病理学诊断进行了评估。进行了描述性统计。使用似然比检验来评估分类变量之间的关联。显著性水平设定为0.05。事后检验用于识别彼此有显著差异的亚组,并应用了Bonferroni校正。儿科患者共诊断出1706例口腔颌面部病变,其中女孩占51.9%。口腔黏液囊肿是最常见的反应性/炎症性病变(64%)。最常受累的部位是嘴唇(34.

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