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与腹膜透析相关的非结核分枝杆菌感染

Non-Tuberculous Mycobacterial Infections Related to Peritoneal Dialysis.

作者信息

Inoue Hiroyuki, Washida Naoki, Morimoto Kohkichi, Shinozuka Keisuke, Kasai Takahiro, Uchiyama Kiyotaka, Tokuyama Hirobumi, Wakino Shu, Itoh Hiroshi

机构信息

Division of Endocrinology, Metabolism and Nephrology, Department of Internal Medicine, School of Medicine, Keio University, Tokyo, Japan

Department of Nephrology, School of Medicine, International University of Health and Welfare, Narita, Chiba, Japan.

出版信息

Perit Dial Int. 2018 Mar-Apr;38(2):147-149. doi: 10.3747/pdi.2017.00172.

Abstract

Most infections related to peritoneal dialysis (PD) are caused by common bacteria, and non-tuberculous mycobacteria are rare. The clinical characteristics and prognosis of PD patients with non-tuberculous mycobacterial infections were investigated at our hospital. Non-tuberculous mycobacteria were detected in 11 patients (exit-site infection, tunnel infection, and peritonitis in 3, 5, and 3 patients, respectively). , , and were identified in 4, 2, and 2 patients, respectively. Most patients with peritonitis or tunnel infection required catheter removal. During the study period (2007 - 2017), peritonitis occurred in 44 patients, including 3 patients (6.8%) with non-tuberculous mycobacterial peritonitis. When non-tuberculous mycobacterial infection occurs, multi-agent antibiotic therapy, unroofing surgery, and/or catheter replacement should be performed to prevent peritonitis.

摘要

大多数与腹膜透析(PD)相关的感染由常见细菌引起,非结核分枝杆菌感染较为罕见。我院对非结核分枝杆菌感染的腹膜透析患者的临床特征及预后进行了调查。11例患者检测到非结核分枝杆菌(分别为3例出口处感染、5例隧道感染和3例腹膜炎)。分别在4例、2例和2例患者中鉴定出[此处原文缺失细菌种类信息]、[此处原文缺失细菌种类信息]和[此处原文缺失细菌种类信息]。大多数腹膜炎或隧道感染患者需要拔除导管。在研究期间(2007 - 2017年),44例患者发生腹膜炎,其中3例(6.8%)为非结核分枝杆菌性腹膜炎。当发生非结核分枝杆菌感染时,应采用多药联合抗生素治疗、开窗手术和/或更换导管以预防腹膜炎。

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