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非结核分枝杆菌病的诊断与治疗方法

Approach to the diagnosis and treatment of non-tuberculous mycobacterial disease.

作者信息

Pennington Kelly M, Vu Ann, Challener Douglas, Rivera Christina G, Shweta F N U, Zeuli John D, Temesgen Zelalem

机构信息

Division of Pulmonary and Critical Care Medicine, Department of Medicine, Mayo Clinic Rochester, MN, USA.

Division of Infectious Diseases, Department of Medicine, Mayo Clinic Rochester, MN, USA.

出版信息

J Clin Tuberc Other Mycobact Dis. 2021 May 8;24:100244. doi: 10.1016/j.jctube.2021.100244. eCollection 2021 Aug.

Abstract

Non-tuberculous mycobacteria (NTM) is a collective name given to a group of more than 190 species of . The clinical presentation for most NTM infections is non-specific, often resulting in delayed diagnosis. Further complicating matters is that NTM organisms can be difficult to isolate. Medications used to treat NTM infection can be difficult for patients to tolerate, and prolonged courses of anti-mycobacterial therapy are often required for adequate suppression or eradication. Herein, we review different NTM syndromes, appropriate diagnostic tests, and treatment regimens.

摘要

非结核分枝杆菌(NTM)是对190多种分枝杆菌的统称。大多数NTM感染的临床表现是非特异性的,常常导致诊断延迟。更复杂的是,NTM微生物很难分离。用于治疗NTM感染的药物患者可能难以耐受,并且通常需要长时间的抗分枝杆菌治疗疗程才能充分抑制或根除感染。在此,我们综述不同的NTM综合征、合适的诊断测试及治疗方案。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/722e/8135042/4b1afaf4e456/gr1.jpg

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