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开放性肾上腺切除术治疗肾上腺神经鞘瘤:一例报告

Adrenal Schwannoma Treated with Open Adrenalectomy: a Case Report.

作者信息

Shivalingaiah Prakash Hebbulse, Kumar Pradeep, Bajoria Suyash

机构信息

Department of Urology, K. R. Hospital, Mysore, Karnataka India.

2Mysore Medical College and Research Institute, Mysore, Karnataka India.

出版信息

Indian J Surg Oncol. 2018 Mar;9(1):83-85. doi: 10.1007/s13193-017-0715-5. Epub 2017 Nov 9.

Abstract

Adrenal schwannomas are very rare tumors accounting for only 0.2% of the adrenal tumors. These are very difficult to diagnose preoperatively and usually present as incidental non-secreting adrenal masses in asymptomatic patients or in patients with non-specific complaints. Computed tomography (CT) and magnetic resonance imaging (MRI) are required to aid the diagnosis, but adrenal schwannomas cannot be distinguishably confirmed on the basis of imaging alone. Histopathological examination (HPE) is essential for accurate diagnosis. We report a rare case of a right adrenal schwannoma in a 68-year-old man. The clinical evaluation was unremarkable and the radiological examination revealed a suprarenal mass lesion on ultrasonography (USG). CT revealed a right adrenal mass which was purported to be likely malignant. Right adrenalectomy was performed by the open approach along with excision of the surrounding enlarged lymph nodes. The postoperative course was uneventful. HPE established the adrenal mass to be a schwannoma, a benign tumor arising from Schwann cells, an exceedingly unusual occurrence in the adrenal glands. A non-secreting adrenal mass can be easily misjudged and the exact diagnosis of the lesion cannot be made sure of without both radiologic and pathologic confirmation. Unilateral adrenal primary or metastatic lesions need pathological confirmation as it can dramatically affect prognosis. Unusual tumors of the adrenal gland like schwannomas may be found incidentally or otherwise and will generate difficulties in establishing the right management. Complete excision is the treatment of choice whenever feasible and will also clarify pathology.

摘要

肾上腺神经鞘瘤是非常罕见的肿瘤,仅占肾上腺肿瘤的0.2%。这些肿瘤术前很难诊断,通常表现为无症状患者或有非特异性主诉患者的偶然发现的无分泌功能的肾上腺肿块。需要计算机断层扫描(CT)和磁共振成像(MRI)来辅助诊断,但仅靠影像学无法明确确诊肾上腺神经鞘瘤。组织病理学检查(HPE)对于准确诊断至关重要。我们报告一例68岁男性右侧肾上腺神经鞘瘤的罕见病例。临床评估无异常,放射学检查在超声检查(USG)中发现肾上腺肿块病变。CT显示右侧肾上腺肿块,据推测可能为恶性。通过开放手术行右侧肾上腺切除术,并切除周围肿大的淋巴结。术后过程顺利。HPE确定肾上腺肿块为神经鞘瘤,这是一种起源于施万细胞的良性肿瘤,在肾上腺中极为罕见。无分泌功能的肾上腺肿块很容易被误诊,没有放射学和病理学的双重确认就无法确定病变的确切诊断。单侧肾上腺原发性或转移性病变需要病理确认,因为这会显著影响预后。像神经鞘瘤这样不常见的肾上腺肿瘤可能偶然发现或以其他方式发现,在确定正确的治疗方案时会产生困难。只要可行,完整切除是首选治疗方法,同时也能明确病理。

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