AlMalki Mussa H, Alotaibi Metib, Ahmad Mohammad Maswood, Rahman Muhammad Amin Ur, Alharthi Turki
Obesity, Endocrine and Metabolism Center, King Fahad Medical City, Riyadh, Saudi Arabia.
King Fahad Medical City, College of Medicine, King Saud Bin Abdul Aziz University for Health Science, Riyadh, Saudi Arabia.
Case Rep Endocrinol. 2020 Jan 30;2020:8020761. doi: 10.1155/2020/8020761. eCollection 2020.
Schwannoma is a benign neurogenic tumor originating from the neural sheath of Schwann cells. It is an extremely rare cause of adrenal adenoma which is very difficult to diagnose preoperatively. We report the case of a right adrenal schwannoma discovered incidentally in a 62-year-old woman during evaluation of right flank pain. The biochemical and hormonal evaluations were unremarkable. Radiological examination revealed a 4.8 cm lesion keeping with right adrenal adenoma. Surgical intervention was done due to the large size of the tumor, and laparoscopic right adrenalectomy was performed. The postoperative course was uneventful. Histological examination established the diagnosis of schwannoma, which was further confirmed by immunohistochemical staining. In conclusion, adrenal schwannoma is extremely rare and can be misdiagnosed as nonsecreting adrenal adenoma. Complete surgical excision is the treatment of choice which is associated with favorable outcome and also helps in clarifying its histopathological nature.
神经鞘瘤是一种起源于施万细胞神经鞘的良性神经源性肿瘤。它是肾上腺腺瘤极其罕见的病因，术前很难诊断。我们报告一例62岁女性在评估右侧腰痛时偶然发现的右肾上腺神经鞘瘤病例。生化和激素评估均无异常。影像学检查发现一个4.8厘米的病变，符合右肾上腺腺瘤表现。由于肿瘤体积较大，进行了手术干预，实施了腹腔镜右肾上腺切除术。术后过程顺利。组织学检查确诊为神经鞘瘤，免疫组化染色进一步证实。总之，肾上腺神经鞘瘤极为罕见，可被误诊为无功能性肾上腺腺瘤。完整的手术切除是首选治疗方法，其预后良好，也有助于明确其组织病理学性质。
