Hung Man, Bounsanga Jerry, Voss Maren W, Saltzman Charles L
Department of Orthopaedic Surgery Operations, University of Utah, Salt Lake City, UT 84108, United States.
World J Orthop. 2018 Mar 18;9(3):41-49. doi: 10.5312/wjo.v9.i3.41.
To establish minimum clinically important difference (MCID) for measurements in an orthopaedic patient population with joint disorders.
Adult patients aged 18 years and older seeking care for joint conditions at an orthopaedic clinic took the Patient-Reported Outcomes Measurement Information System Physical Function (PROMIS PF) computerized adaptive test (CAT), hip disability and osteoarthritis outcome score for joint reconstruction (HOOS JR), and the knee injury and osteoarthritis outcome score for joint reconstruction (KOOS JR) from February 2014 to April 2017. MCIDs were calculated using anchor-based and distribution-based methods. Patient reports of meaningful change in function since their first clinic encounter were used as an anchor.
There were 2226 patients who participated with a mean age of 61.16 (SD = 12.84) years, 41.6% male, and 89.7% Caucasian. Mean change ranged from 7.29 to 8.41 for the PROMIS PF CAT, from 14.81 to 19.68 for the HOOS JR, and from 14.51 to 18.85 for the KOOS JR. ROC cut-offs ranged from 1.97-8.18 for the PF CAT, 6.33-43.36 for the HOOS JR, and 2.21-8.16 for the KOOS JR. Distribution-based methods estimated MCID values ranging from 2.45 to 21.55 for the PROMIS PF CAT; from 3.90 to 43.61 for the HOOS JR, and from 3.98 to 40.67 for the KOOS JR. The median MCID value in the range was similar to the mean change score for each measure and was 7.9 for the PF CAT, 18.0 for the HOOS JR, and 15.1 for the KOOS JR.
This is the first comprehensive study providing a wide range of MCIDs for the PROMIS PF, HOOS JR, and KOOS JR in orthopaedic patients with joint ailments.
确定在患有关节疾病的骨科患者群体中测量指标的最小临床重要差异（MCID）。
2014年2月至2017年4月期间，在骨科诊所寻求关节疾病治疗的18岁及以上成年患者接受了患者报告结局测量信息系统身体功能（PROMIS PF）计算机自适应测试（CAT）、关节重建的髋关节残疾和骨关节炎结局评分（HOOS JR）以及关节重建的膝关节损伤和骨关节炎结局评分（KOOS JR）。使用基于锚定和基于分布的方法计算MCID。患者自首次就诊以来功能有意义变化的报告用作锚定。
共有2226名患者参与，平均年龄为61.16（标准差 = 12.84）岁，男性占41.6%，白种人占89.7%。PROMIS PF CAT的平均变化范围为7.29至8.41，HOOS JR为14.81至19.68，KOOS JR为14.51至18.85。PF CAT的ROC临界值范围为1.97 - 8.18，HOOS JR为6.33 - 43.36，KOOS JR为2.21 - 8.16。基于分布的方法估计PROMIS PF CAT的MCID值范围为2.45至21.55；HOOS JR为3.90至43.61，KOOS JR为3.98至40.67。该范围内的MCID中位数与各测量指标的平均变化得分相似，PF CAT为7.9，HOOS JR为18.0，KOOS JR为15.1。
这是第一项全面研究，为患有关节疾病的骨科患者提供了PROMIS PF、HOOS JR和KOOS JR的广泛MCID。
