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老年人不适当用药及依从性评估

Evaluation of Inappropriate Medication Use and Compliance in Elderly People.

作者信息

Yilmaz Fikriye, Colak Meric Yavuz

机构信息

Department of Health Care Management, Faculty of Health Sciences, Baskent University, Ankara, Turkey.

出版信息

Curr Drug Saf. 2018;13(2):122-127. doi: 10.2174/1574886313666180321120036.

Abstract

OBJECTIVE

The aim of this study is to evaluate the potentially inappropriate medication use and medication compliance in elderly patients who buy prescribed drugs from a pharmacy in Ankara.

METHODS

In this cross-sectional field study, 200 older people who bought prescribed drugs from a pharmacy which is close to several hospitals in Ankara in April 2016 were chosen as random sample. A questionnaire consisting of questions related to socio-demographic characteristics, health status, drug use of elderly and Morisky Green Levine Medication Adherence Scale (MGLS) was used to collect data. The appropriateness of the drugs prescribed for elderly was determined by the pharmacist according to Beers criteria. The data were evaluated by descriptive statistics and Chi-Square test.

RESULTS

57.4% of the 200 elderly patients in the study are women and the mean age is 72.55 ± 6.34 years; 72.6% of them are below high school. When the medication compliance was examined, 36.3% of them did not comply with the drug treatment according to MGLS. It was determined that having sufficient information about the drug, education level, occupation and polymorbidity affect medication adherence (p <0.05). When the appropriateness evaluated according to Beers Criteria, 41.7% of the subjects were prescribed potentially inappropriate medications (PIM). According to the analysis, the number of drugs prescribed and the type of the chronic disease have effects on the inappropriate prescription (p <0.05).

CONCLUSION

According to the study, the prevalence of inappropriate medication use in the elderly is higher than the medication non-adherence.

摘要

目的

本研究旨在评估在安卡拉从药房购买处方药的老年患者中潜在不适当用药情况及用药依从性。

方法

在这项横断面实地研究中,随机选取了200名于2016年4月在安卡拉几家医院附近的一家药房购买处方药的老年人作为样本。使用一份包含与社会人口统计学特征、健康状况、老年人用药情况以及莫利斯基 - 格林 - 莱文用药依从性量表(MGLS)相关问题的问卷来收集数据。药剂师根据Beers标准确定为老年人开具的药物是否恰当。数据采用描述性统计和卡方检验进行评估。

结果

研究中的200名老年患者中,57.4%为女性,平均年龄为72.55±6.34岁;其中72.6%的人学历低于高中。在检查用药依从性时,根据MGLS,36.3%的患者未遵医嘱服药。结果确定,对药物有足够了解、教育水平、职业和多种疾病共存会影响用药依从性(p<0.05)。根据Beers标准评估药物恰当性时,41.7%的受试者被开具了潜在不适当药物(PIM)。经分析,所开药物数量和慢性病类型对不适当处方有影响(p<0.05)。

结论

根据该研究,老年人中不适当用药的发生率高于用药不依从率。

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