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近视性黄斑劈裂中保留与不保留黄斑中心凹的内界膜剥除术的长期预后

Long-term outcome of internal limiting membrane peeling with and without foveal sparing in myopic foveoschisis.

作者信息

Elwan Mohammed Mamdouh, Abd Elghafar Ayman Elsayed, Hagras Sherein Mahmoud, Abou Samra Waleed Ali, Saleh Sameh Mohamed

机构信息

Mansoura Ophthalmic Center, Department of Ophthalmology, Faculty of Medicine, Mansoura University, Mansoura, Egypt.

出版信息

Eur J Ophthalmol. 2019 Jan;29(1):69-74. doi: 10.1177/1120672117750059. Epub 2018 Mar 22.

Abstract

PURPOSE

: To compare between vitrectomy with internal limiting membrane peeling over the whole macula and preservation of the epi-foveal internal limiting membrane in myopic foveoschisis.

PATIENTS AND METHODS

: A prospective controlled non- randomized comparative study included patients with myopic foveoschisis recruited between 2013 and 2017. Patients were allocated into two groups: group A included patients who underwent vitrectomy with complete macular internal limiting membrane peeling and group B included those who underwent preservation of the epi-foveal membrane. Pre- and postoperative best corrected visual acuity and macular optical coherence tomography were obtained and compared.

RESULTS

: There was no statistically significant difference between the two groups regarding the preoperative baseline data. The difference between the two groups was insignificant as regard postoperative best corrected visual acuity (p = 0.18) and central foveal thickness (p =0.504). There was statistically significant improvement in final best corrected visual acuity within each group (p < 0.0001). Central foveal thickness significantly decreased postoperatively within each group (p < 0.001). No macular holes or other visual-threatening complications were recorded in either group.

CONCLUSION

: Vitrectomy with complete internal limiting membrane peeling resulted in comparable outcomes to those achieved with preservation of the epi-foveal membrane in treating cases with myopic foveoschisis. There was no statistically significant difference in final visual acuity between the two groups. No macular holes were recorded in either group.

摘要

目的

比较在高度近视性黄斑劈裂患者中,行全黄斑区视网膜内界膜剥除的玻璃体切除术与保留黄斑中心凹视网膜内界膜的玻璃体切除术的效果。

患者与方法

一项前瞻性对照非随机比较研究纳入了2013年至2017年期间招募的高度近视性黄斑劈裂患者。患者被分为两组:A组包括接受全黄斑区视网膜内界膜剥除玻璃体切除术的患者,B组包括接受保留黄斑中心凹视网膜内界膜玻璃体切除术的患者。获取并比较术前和术后的最佳矫正视力及黄斑光学相干断层扫描结果。

结果

两组术前基线数据无统计学显著差异。两组术后最佳矫正视力(p = 0.18)和黄斑中心凹厚度(p = 0.504)的差异无统计学意义。每组最终最佳矫正视力均有统计学显著改善(p < 0.0001)。每组术后黄斑中心凹厚度均显著降低(p < 0.001)。两组均未记录到黄斑裂孔或其他威胁视力的并发症。

结论

在治疗高度近视性黄斑劈裂病例时,行完全视网膜内界膜剥除的玻璃体切除术与保留黄斑中心凹视网膜内界膜的玻璃体切除术效果相当。两组最终视力无统计学显著差异。两组均未记录到黄斑裂孔。

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