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[卵巢上皮癌的治疗。支持在化疗和放疗前进行原发性根治性和区域性手术]

[Treatment of epithelial cancer of the ovary. In favor of primary radical and regional surgery before chemotherapy and radiotherapy].

作者信息

Joyeux H, Saint-Aubert B, Gouttebel M C, Zhang G H, Domergue J, Dubois J B, Cupissol D

出版信息

Presse Med. 1987;16(27):1325-8.

PMID:2956592
Abstract

The treatment of epithelial carcinoma of the ovary (90% of malignant ovarian tumours) has largely benefited from chemotherapy, notably since the advent of cisplatinum. Radiotherapy may be an important adjuvant treatment to sterilize the pelvis. Both chemo- and radiotherapy are effective mainly on small residual diseases, hence the importance of initial surgery with maximal cell reduction, notably in carcinomas classified as stage III according to the International Gynaecology and Obstetrics Federation system. Regional surgery of the ovary must be pelvic and abdominal: from Douglas' pouch to the diaphragmatic domes. This therapeutic approach requires the resolution of two problems: intensive care and post-operative feeding. It has 2 major advantages: it avoids second-look operations or reduces their number, and it increases the survival rate at 5 years.

摘要

卵巢上皮癌(占恶性卵巢肿瘤的90%)的治疗在很大程度上受益于化疗,尤其是自顺铂问世以来。放疗可能是使盆腔灭菌的重要辅助治疗方法。化疗和放疗主要对小的残留病灶有效,因此初始手术尽可能减少肿瘤细胞数量非常重要,特别是对于根据国际妇产科联盟系统分类为III期的癌。卵巢的区域手术必须包括盆腔和腹部:从Douglas窝到膈肌穹窿。这种治疗方法需要解决两个问题:重症监护和术后喂养。它有两个主要优点:避免二次探查手术或减少其数量,并提高5年生存率。

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Presse Med. 1987;16(27):1325-8.
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