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草甘膦的致癌性:为何新西兰环境保护局深陷困境?

Carcinogenicity of glyphosate: why is New Zealand's EPA lost in the weeds?

作者信息

Douwes Jeroen, 't Mannetje Andrea, McLean Dave, Pearce Neil, Woodward Alistair, Potter John D

机构信息

Centre for Public Health Research, Massey University, Wellington.

Department of Medical Statistics, London School of Hygiene and Tropical Medicine, United Kingdom.

出版信息

N Z Med J. 2018 Mar 23;131(1472):82-89.

Abstract

In 2015, the International Agency for Research on Cancer (IARC) concluded that glyphosate is "probably carcinogenic to humans". The New Zealand Environmental Protection Authority (NZEPA) rejected this and commissioned a new report, concluding that glyphosate was unlikely to be genotoxic or carcinogenic to humans. The NZEPA has argued that the difference arose because IARC is a "hazard-identification authority", whereas NZEPA is a "regulatory body that needs to cast the net more widely". We conclude that the NZEPA process for evaluating the carcinogenicity of glyphosate was flawed and the post hoc justification invalid: there is no mention of risk assessment or "net-benefit approach" in the NZEPA report; and there is no discussion of current New Zealand glyphosate exposures. Further, the NZEPA report quotes heavily from the European Food Safety Authority (EFSA) report, which is itself markedly flawed, and like the NZEPA report, relies heavily on industry-funded and industry-manipulated reviews. Given the scientific flaws in both reports we urge that: the NZEPA report be withdrawn; the NZEPA respond to the concerns raised and for a reassessment to be conducted; and clearer process and better understanding of science be used to inform any future review of hazardous substances in New Zealand.

摘要

2015年,国际癌症研究机构(IARC)得出结论,草甘膦“对人类可能致癌”。新西兰环境保护局(NZEPA)对此予以否认,并委托撰写了一份新报告,得出草甘膦对人类不太可能具有基因毒性或致癌性的结论。NZEPA辩称,产生这种差异的原因是IARC是一个“危害识别机构”,而NZEPA是一个“需要更广泛考虑问题的监管机构”。我们认为,NZEPA评估草甘膦致癌性的过程存在缺陷,事后的理由也站不住脚:NZEPA的报告中没有提及风险评估或“净效益方法”;也没有讨论新西兰目前草甘膦的接触情况。此外,NZEPA的报告大量引用了欧洲食品安全局(EFSA)的报告,而该报告本身就存在明显缺陷,并且与NZEPA的报告一样,严重依赖行业资助和行业操纵的审查。鉴于两份报告都存在科学缺陷,我们敦促:撤回NZEPA的报告;NZEPA回应所提出的关切并进行重新评估;采用更清晰的流程和对科学的更好理解,为新西兰未来对有害物质的任何审查提供参考。

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