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SPRINT研究之后:无人值守自动诊室血压测量与24小时血压监测的进一步比较

In the aftermath of SPRINT: further comparison of unattended automated office blood pressure measurement and 24-hour blood pressure monitoring.

作者信息

Seidlerová Jitka, Gelžinský Julius, Mateřánková Markéta, Ceral Jiří, König Petr, Filipovský Jan

机构信息

a Internal Department II, Faculty of Medicine in Pilsen , Charles University , Hradec Králové , Czech Republic.

b Biomedical Centre, Faculty of Medicine in Pilsen , Charles University , Hradec Králové , Czech Republic.

出版信息

Blood Press. 2018 Oct;27(5):256-261. doi: 10.1080/08037051.2018.1454258. Epub 2018 Mar 22.

DOI:10.1080/08037051.2018.1454258
PMID:29566565
Abstract

AIMS

Several papers reported that unattended automated office blood pressure (uAutoOBP) is closely related to daytime ambulatory blood pressure monitoring (ABPM). In the present study, we aim to study uAutoOBP and its relation to 24-hour ABPM and ABPM variability.

MATERIAL AND METHODS

Stable treated hypertensive subjects were examined in two Czech academic hypertension centres. uAutoOBP was measured with the BP Tru device; attended BP three times with auscultatory method (AuscOBP) by the physician. ABPM was performed within one week from the clinical visit.

RESULTS

Data on 98 subjects aged 67.7 ± 9.3 years with 24-hour ABPM 120.3 ± 10.6/72.7 ± 7.9 mm Hg are reported. uAutoOBP was lower than 24-hour (by -5.2 ± 11.3/-0.5 ± 6.9 mm Hg) and daytime (by -6.7 ± 12.82.4 ± 8.0 mm Hg) ABPM and the individual variability of the difference was very large (up to 30 mm Hg). The correlation coefficients between ABPM and uAutoOBP were similar compared to AuscOBP (p ≥ .17). Variability of uAutoOBP, but not AuscOBP, readings during one clinical visit was related to short-term blood pressure variability of ABPM. The difference between AuscOBP and uAutoOBP was larger in patients with white-coat effect compared to other blood pressure control groups (25.1 ± 7.0 vs. 2.2 ± 10.3 mm Hg; p = .0036).

CONCLUSIONS

Our study shows that uAutoOBP is not good predictor of ambulatory blood pressure monitoring, not even of the daytime values. It might, however, indicate short-term blood pressure variability and, when compared with AuscOBP, also detect patients with white-coat effect.

摘要

目的

多篇论文报道,无人值守自动诊室血压(uAutoOBP)与日间动态血压监测(ABPM)密切相关。在本研究中,我们旨在研究uAutoOBP及其与24小时ABPM和ABPM变异性的关系。

材料与方法

在两个捷克学术性高血压中心对病情稳定的高血压患者进行检查。使用BP Tru设备测量uAutoOBP;医生采用听诊法(AuscOBP)测量三次诊室血压。在临床就诊后一周内进行ABPM。

结果

报告了98名年龄为67.7±9.3岁的受试者的数据,其24小时ABPM为120.3±10.6/72.7±7.9 mmHg。uAutoOBP低于24小时ABPM(低5.2±11.3/-0.5±6.9 mmHg)和日间ABPM(低6.7±12.8/2.4±8.0 mmHg),且差值的个体变异性非常大(高达30 mmHg)。与AuscOBP相比,ABPM与uAutoOBP之间的相关系数相似(p≥0.17)。一次临床就诊期间uAutoOBP读数的变异性与ABPM的短期血压变异性相关,但AuscOBP读数的变异性与之无关。与其他血压控制组相比,白大衣效应患者的AuscOBP与uAutoOBP之间的差异更大(25.1±7.0 vs. 2.2±10.3 mmHg;p = 0.0036)。

结论

我们的研究表明,uAutoOBP不是动态血压监测的良好预测指标,甚至对日间值也不是。然而,它可能表明短期血压变异性,并且与AuscOBP相比,还能检测出有白大衣效应的患者。

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