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一项关于接受治疗的高血压患者无人值守自动诊室血压测量的多中心研究。

A multicentre study on unattended automated office blood pressure measurement in treated hypertensive patients.

作者信息

Filipovský Jan, Seidlerová Jitka, Ceral Jiří, Vysočanová Petra, Špác Jiří, Souček Miroslav, Řiháček Ivan, Mateřánková Markéta, König Petr, Rosolová Hana

机构信息

a Internal Department II, Faculty of Medicine in Pilsen , Charles University , Plzen , Czech Republic.

b Biomedical Centre, Faculty of Medicine in Pilsen , Charles University , Plzen , Czech Republic.

出版信息

Blood Press. 2018 Aug;27(4):188-193. doi: 10.1080/08037051.2018.1425606. Epub 2018 Jan 15.

DOI:10.1080/08037051.2018.1425606
PMID:29334262
Abstract

AIMS

Unattended automated office blood pressure (uAutoOBP) may eliminate white-coat effect. In the present study, we studied its relationships to attended office blood pressure (BP) and ambulatory BP monitoring (ABPM).

MATERIAL AND METHODS

Stable treated hypertensive subjects were examined in four Czech academic hypertension centres. uAutoOBP was measured with the BP Tru device; attended BP was measured six times: three times with auscultatory method (AuscOBP) by the physician followed optionally by three oscillometric measurements (OscOBP). ABPM was performed within one week from the clinical visit.

RESULTS

Data on 172 subjects aged 63.7 ± 12.4 years with AuscOBP 127.6 ± 12.1/77.6 ± 10.0 mm Hg are reported. uAutoOBP was by 8.5 ± 9.0/3.0 ± 6.1 mm Hg lower than AuscOBP. The AuscOBP-uAutoOBP difference increased with the AuscOBP level and it did not depend on any other factor. OscOBP differed by 8.6 ± 8.6/1.9 ± 5.7 mm Hg from uAutoOBP. 24-hour mean BP was by 4.2 ± 12.1/3.5 ± 7.8 mm Hg lower than AuscOBP and by 4.3 ± 11.0/0.5 ± 6.9 mm Hg higher than uAutoOBP; the correlation coefficients of 24-hour mean BP with AuscOBP and with uAutoOBP did not differ (p for difference ≥.13). In the lowest BP group (systolic AuscOBP <120 mm Hg or diastolic AuscOBP <70 mm Hg), both AuscOBP and uAutoOBP were lower than 24-hour mean BP, while in the highest BP group (systolic AuscOBP ≥140 mm Hg or diastolic AuscOBP ≥90 mm Hg), they were higher.

CONCLUSIONS

Compared to uAutoOBP, attended BP measurement gives higher values, both when measured with auscultatory or oscillometric method. Inter-individual variability of AutoOBP - uAuscOBP difference, as well of uAutoOBP - ABPM difference, is large. We did not prove that uAutoOBP would be associated to 24-hour ambulatory BP more closely than attended BP.

摘要

目的

无人值守自动诊室血压(uAutoOBP)可能消除白大衣效应。在本研究中,我们探讨了其与诊室血压(BP)及动态血压监测(ABPM)之间的关系。

材料与方法

在四个捷克学术性高血压中心对病情稳定的高血压患者进行检查。使用BP Tru设备测量uAutoOBP;诊室血压测量六次:医生用听诊法测量三次(AuscOBP),之后可选择用示波法测量三次(OscOBP)。在临床就诊后一周内进行ABPM。

结果

报告了172例年龄为63.7±12.4岁、听诊法测量的诊室血压为127.6±12.1/77.6±10.0 mmHg的患者的数据。uAutoOBP比听诊法测量的诊室血压低8.5±9.0/3.0±6.1 mmHg。听诊法测量的诊室血压与uAutoOBP的差值随听诊法测量的诊室血压水平升高而增大,且不受其他任何因素影响。示波法测量的诊室血压与uAutoOBP相差8.6±8.6/1.9±5.7 mmHg。24小时平均血压比听诊法测量的诊室血压低4.2±12.1/3.5±7.8 mmHg,比uAutoOBP高4.3±11.0/0.5±6.9 mmHg;24小时平均血压与听诊法测量的诊室血压及uAutoOBP的相关系数无差异(差异p≥0.13)。在血压最低组(听诊法测量的收缩压<120 mmHg或舒张压<70 mmHg),听诊法测量的诊室血压及uAutoOBP均低于24小时平均血压,而在血压最高组(听诊法测量的收缩压≥140 mmHg或舒张压≥90 mmHg),二者均高于24小时平均血压。

结论

与uAutoOBP相比,无论是用听诊法还是示波法测量,诊室血压测量值都更高。自动诊室血压与听诊法测量的诊室血压差值以及uAutoOBP与动态血压监测差值的个体间变异性都很大。我们并未证实uAutoOBP与24小时动态血压的相关性比诊室血压更密切。

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