Department of Epidemiology and Health Statistics, School of Public Health, Anhui Medical University, Hefei, Anhui Province, China.
Anhui Mental Health Centre, Hefei, Anhui Province, China.
Public Health. 2018 Jun;159:70-77. doi: 10.1016/j.puhe.2018.01.032. Epub 2018 Mar 19.
To investigate the relationship between ambient temperature and hospital admissions for schizophrenia in Hefei, China.
An ecological design was used to explore the effect of ambient temperature on hospital admissions for schizophrenia.
Daily data on hospital admissions for schizophrenia and meteorological data for the warm season (May-October) in 2005-2014 were obtained from Anhui Mental Health Centre and Hefei Bureau of Meteorology, respectively. Poisson generalised linear regression model combined with a distributed lag non-linear model was used to analyse the effects of temperature on admissions for schizophrenia. Stratified analyses according to individual characteristics, such as age and sex, were also conducted.
A significant relationship was found between ambient temperature and admissions for schizophrenia. High temperature appeared to have a delayed effect on admissions for schizophrenia, and a temperature of 28°C (75th percentile) at lag 0-4 days was associated with a 7% (95% confidence interval: 4-11%) increase in admissions for schizophrenia. Stratified analyses showed that male patients, patients aged 21-60 years and married patients were more vulnerable to high temperature, and the temperature effects for those groups occurred at a lag of 1 day.
High temperature poses significant risks for schizophrenia in subtropical regions. Future preventive measures for reducing the occurrence of schizophrenia should be considered for susceptible populations.
探讨中国合肥市环境温度与精神分裂症住院的关系。
采用生态设计探讨环境温度对精神分裂症住院的影响。
分别从安徽省精神卫生中心和合肥市气象局获取 2005-2014 年暖季（5-10 月）的每日精神分裂症住院数据和气象数据。采用泊松广义线性回归模型结合分布滞后非线性模型分析温度对精神分裂症住院的影响。根据个体特征（如年龄和性别）进行分层分析。
环境温度与精神分裂症住院之间存在显著关系。高温对精神分裂症住院似乎有延迟效应，滞后 0-4 天的 28°C（第 75 百分位数）温度与精神分裂症住院增加 7%（95%置信区间：4-11%）相关。分层分析显示，男性患者、21-60 岁患者和已婚患者对高温更为敏感，这些人群的温度效应出现在滞后 1 天。
高温对亚热带地区的精神分裂症构成重大风险。未来应考虑针对易感人群采取预防措施，以减少精神分裂症的发生。
