Johnston Steven
Balfour Oral Surgery Unit, NHS Orkney, Balfour Hospital, Kirkwall, Orkney KW15 1BH, Scotland, UK.
Dent J (Basel). 2015 Oct 6;3(4):102-110. doi: 10.3390/dj3040102.
Novel oral antiplatelet (NOAP) (prasugrel and ticagrelor) and direct oral anticoagulant drugs (DOAC) (dabigatran, rivaroxaban and apixaban) have emerged in the last decade. This study was undertaken to determine current approaches taken to the management of patients taking these agents in dental practice in a remote and rural setting.
A small retrospective study was carried out in a small island population that identified patients taking one of the above drugs. All national health service and private dental records were examined to determine the type of treatment carried out and whether drug therapy, treatment plans or actual treatment were modified as a result of NOAP or DOAC therapy. In addition other outcomes such as referral to another service for advice or treatment and any adverse bleeding events were noted.
156 dental encounters for 95 patients taking one of the drugs were identified. Significant events were identified in sixteen encounters and the management of patients taking each drug type differed significantly between cases but no patients returned with troublesome post-operative bleeding.
The approaches taken by dental surgeons in Orkney in the management of the NOAPs and DOACs varied and this is likely to be a reflection of the limited literature available.
新型口服抗血小板药物(NOAP,普拉格雷和替格瑞洛)以及直接口服抗凝药物(DOAC,达比加群、利伐沙班和阿哌沙班)在过去十年中出现。本研究旨在确定在偏远农村地区的牙科实践中,对服用这些药物的患者进行管理的当前方法。
在一个小岛屿人群中进行了一项小型回顾性研究,确定服用上述药物之一的患者。检查了所有国家医疗服务和私人牙科记录,以确定所进行的治疗类型,以及NOAP或DOAC治疗是否导致药物治疗、治疗计划或实际治疗发生改变。此外,还记录了其他结果,如转介至另一服务机构寻求建议或治疗,以及任何不良出血事件。
确定了95名服用其中一种药物的患者的156次牙科诊疗情况。在16次诊疗中发现了重大事件,服用每种药物类型的患者管理在病例之间存在显著差异,但没有患者术后出现严重出血而返回。
奥克尼群岛的牙科外科医生对NOAP和DOAC的管理方法各不相同,这可能反映了现有文献的局限性。