Tonpitak Walaiporn, Pathomsakulwong Watcharapol, Sornklien Chulabha, Krajaejun Theerapong, Wutthiwithayaphong Suppathat
Department of Microbiology, Faculty of Veterinary Medicine, Mahanakorn University of Technology, Bangkok, Thailand.
Equine Clinic, Faculty of Veterinary Medicine, Kasetsart University, Kamphaeng Saen campus, Nakhon Pathom, Thailand.
JMM Case Rep. 2018 Jan 9;5(1):e005136. doi: 10.1099/jmmcr.0.005136. eCollection 2018 Jan.
Pythiosis is caused by , a fungus-like organism in the class . It can infect humans and a variety of animal species in tropical, subtropical and some temperate regions. Cases of animal pythiosis have occurred predominantly in horses in the skin and subcutaneous tissue at the limbs and in the ventral portion of thoracoabdominal wall - lesions in the nasal region are rarely reported. Moreover, although many human pythiosis cases have been reported in Thailand, no cases of animal pythiosis in Thailand have been reported.
We report a case of pythiosis in a horse infected at the nasal cavity. Diagnosis was performed by zoospore formation by bait technique, immunohistochemical stain, immunochromatography and sequence analysis.
The sequences of rDNA were 99 % and 96 to 99 % identical to GenBank isolates of from two Thai human patients and horses from various countries, respectively. This represents the first confirmed report of nasal equine pythiosis in Thailand.
腐霉病由 纲中的一种类真菌生物引起。它可在热带、亚热带和一些温带地区感染人类及多种动物物种。动物腐霉病病例主要发生在马身上，病变位于四肢的皮肤和皮下组织以及胸腹壁的腹侧部分，鼻腔区域的病变鲜有报道。此外，尽管泰国已报道了许多人类腐霉病病例，但泰国尚未报道过动物腐霉病病例。
我们报告一例鼻腔感染腐霉病的马病例。通过诱饵技术观察游动孢子形成、免疫组织化学染色、免疫层析和序列分析进行诊断。
核糖体DNA序列分别与来自两名泰国人类患者和不同国家马匹的 基因库分离株有99%以及96%至99%的同源性。这是泰国首例经证实的马鼻腔腐霉病报告。
