Wessling J
Klinik für diagnostische und interventionelle Radiologie und Neuroradiologie, Clemenshospital Münster, Düesbergweg 124, 48153, Münster, Deutschland.
Radiologe. 2018 Apr;58(4):302-311. doi: 10.1007/s00117-018-0379-3.
Computed tomography (CT) is often used as the initial diagnostic test in patients with inflammatory and infectious types of enterocolitis. The differential diagnosis is broad, including infectious, non-infectious and vascular causes, which have substantially different management strategies. Although a definitive diagnosis often relies on endoscopic biopsy results, stool culture results or other clinical features, radiologists often help to guide the diagnosis.
This article reviews the CT appearance of different infectious and inflammatory forms of enterocolitis. General and specific intramural and extramural CT findings in the small bowel and colon are discussed. Added focus is placed on distribution patterns and medication side effects that can act as important diagnostic clues.
Infectious enterocolitis is due to bowel inflammation caused by bacteria, viruses, or parasites, which show a preferential localization. Pancolitis can be seen with Clostridium difficile with the relatively specific CT finding of the "giraffe coat" sign. Inflammatory enterocolitis can be primary (inflammatory bowel disease, vasculitis) or secondary (radiation therapy, graft versus host disease etc.). Ischemic colitis and enteritis can result from arterial compromise, low flow states that globally reduce perfusion or venous insufficiency. The CT appearance varies depending on the cause, the time of onset and grade of reperfusion.
Knowledge of characteristic mural and extramural CT of MRI findings, geographic distributions and therapy effects help to guide the differential diagnostics in inflammatory and infectious types of enterocolitis.
计算机断层扫描(CT)常被用作炎症性和感染性肠炎患者的初始诊断检查。鉴别诊断范围广泛,包括感染性、非感染性和血管性病因,它们具有截然不同的治疗策略。尽管明确诊断通常依赖于内镜活检结果、粪便培养结果或其他临床特征,但放射科医生常有助于指导诊断。
本文综述了不同感染性和炎症性肠炎的CT表现。讨论了小肠和结肠壁内及壁外的一般和特异性CT表现。重点关注可作为重要诊断线索的分布模式和药物副作用。
感染性肠炎是由细菌、病毒或寄生虫引起的肠道炎症,具有特定的好发部位。艰难梭菌感染可导致全结肠炎,CT表现有相对特异的“长颈鹿皮”征。炎症性肠炎可分为原发性(炎症性肠病、血管炎)或继发性(放射治疗、移植物抗宿主病等)。缺血性结肠炎和肠炎可由动脉供血不足、导致整体灌注减少的低血流状态或静脉功能不全引起。CT表现因病因、发病时间和再灌注程度而异。
了解CT或MRI特征性的壁内和壁外表现、病变分布及治疗效果有助于指导炎症性和感染性肠炎的鉴别诊断。