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在退化的外科主动脉瓣中进行CoreValve Evolut R瓣膜中置瓣膜植入术。

Valve in valve implantation of the CoreValve Evolut R in degenerated surgical aortic valves.

作者信息

Schwerg Marius, Stangl Karl, Laule Michael, Stangl Verena, Dreger Henryk

机构信息

Department of Cardiology, Charité - Universitätsmedizin Berlin, Campus Mitte, Berlin, Germany, Germany.

出版信息

Cardiol J. 2018;25(3):301-307. doi: 10.5603/CJ.a2018.0004. Epub 2018 Mar 23.

Abstract

BACKGROUND

The new CoreValve Evolut R has an improved design to minimize paravalvular leak-age and allows repositioning of the valve. For patients with degenerated bioprosthetic aortic valves, transcatheter aortic valve implantation (TAVI) represents a less invasive option. Herein reported are valve-in-valve (ViV) implantations of this new valve.

METHODS

A total of 26 patients (mean age 79.4 ± 6.1 years, 17 males and 9 females) were treated for severe prosthesis stenosis (n = 9), severe regurgitation (n = 8) or severe combination of stenosis and regurgitation (n = 9). All patients underwent transthoracic echocardiography before and after ViV implantation.

RESULTS

Valve-in-valve implantation of a CoreValve Evolut R was performed successfully in all pa-tients. The mean transaortic gradient for stenotic valves determined by transthoracic echocardiography was reduced significantly from 37.5 ± 15.3 mmHg in patients with prosthesis stenosis to 16.3 ± 8.2 mmHg (p < 0.001). In all cases with severe prosthesis regurgitation, regurgitation was reduced to none or mild. All-cause mortality after 30 days was 0%.

CONCLUSIONS

It was concluded that CoreValve Evolut R is well suited for ViV implantation.

摘要

背景

新型CoreValve Evolut R瓣膜设计有所改进,可将瓣周漏降至最低,并允许瓣膜重新定位。对于生物人工主动脉瓣退化的患者,经导管主动脉瓣植入术(TAVI)是一种侵入性较小的选择。本文报道了这种新型瓣膜的瓣中瓣(ViV)植入情况。

方法

共有26例患者(平均年龄79.4±6.1岁,男性17例,女性9例)因严重人工瓣膜狭窄(n = 9)、严重反流(n = 8)或严重的狭窄与反流合并情况(n = 9)接受治疗。所有患者在ViV植入前后均接受经胸超声心动图检查。

结果

所有患者均成功进行了CoreValve Evolut R瓣膜的瓣中瓣植入。经胸超声心动图测定的狭窄瓣膜的平均跨主动脉压差从人工瓣膜狭窄患者的37.5±15.3 mmHg显著降至16.3±8.2 mmHg(p < 0.001)。在所有严重人工瓣膜反流的病例中,反流均减轻至无或轻度。30天全因死亡率为0%。

结论

得出结论,CoreValve Evolut R非常适合瓣中瓣植入。

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