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法国停止卡介苗强制性免疫后儿童非结核分枝杆菌淋巴结炎的出现。

Emergence of Nontuberculous Mycobacterial Lymphadenitis in Children After the Discontinuation of Mandatory Bacillus Calmette and GuÉrin Immunization in France.

机构信息

From the Infectious Diseases.

Bacteriology, Pontchaillou University Hospital, Rennes, France.

出版信息

Pediatr Infect Dis J. 2018 Oct;37(10):e257-e260. doi: 10.1097/INF.0000000000001977.

Abstract

Eighty-five children were diagnosed with culture-confirmed nontuberculous mycobacterial cervical lymphadenitis within the MYCOMED surveillance network from 2004 to 2013. The mean incidence sharply increased from 0.57 to 3.7 per 100,000 children per year, after the discontinuation of mandatory bacillus Calmette and Guérin immunization in 2007. Cases were documented as Mycobacterium avium (62.3%), Mycobacterium intracellulare (15.3%) and Mycobacterium lentiflavum (12.9%). Outcome was favorable in all, with or without surgery or antimycobacterial treatment.

摘要

2004 年至 2013 年间,在 MYCOMED 监测网络中,85 名儿童被确诊患有经培养证实的非结核分枝杆菌性颈淋巴结炎。2007 年停止卡介苗强制免疫后,发病率均值从每年每 10 万人 0.57 例急剧上升至 3.7 例。病例被记录为鸟分枝杆菌(62.3%)、胞内分枝杆菌(15.3%)和微黄分枝杆菌(12.9%)。所有病例均无需手术或抗分枝杆菌治疗即可痊愈。

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